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4DDG

Crystal structure of human OTUB1/UbcH5b~Ub/Ub

Summary for 4DDG
Entry DOI10.2210/pdb4ddg/pdb
Related4DDI
DescriptorUbiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1, Polyubiquitin-C (2 entities in total)
Functional Keywordsinhibition, hydrolase-ligase complex, hydrolase/ligase
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm : Q96FW1
Ubiquitin: Cytoplasm : P0CG48
Total number of polymer chains18
Total formula weight377617.23
Authors
Juang, Y.C.,Sanches, M.,Sicheri, F. (deposition date: 2012-01-18, release date: 2012-02-22, Last modification date: 2023-09-13)
Primary citationJuang, Y.C.,Landry, M.C.,Sanches, M.,Vittal, V.,Leung, C.C.,Ceccarelli, D.F.,Mateo, A.R.,Pruneda, J.N.,Mao, D.Y.,Szilard, R.K.,Orlicky, S.,Munro, M.,Brzovic, P.S.,Klevit, R.E.,Sicheri, F.,Durocher, D.
OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function.
Mol.Cell, 45:384-397, 2012
Cited by
PubMed: 22325355
DOI: 10.1016/j.molcel.2012.01.011
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2987 Å)
Structure validation

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