4DDG

Crystal structure of human OTUB1/UbcH5b~Ub/Ub

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, J, K...	Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1	polymer	399	45782.5	6	UniProt (P62837) UniProt (Q96FW1) Pfam (PF00179) Pfam (PF10275) In PDB	Homo sapiens (human)	Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2(17)KB 2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2, Deubiquitinating enzyme OTUB1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Otubain-1, hOTU1, Ubiquitin-specific-processing protease OTUB1
2	D, E, F, G, H...	Polyubiquitin-C	polymer	76	8576.8	12	UniProt (P0CG48) Pfam (PF00240) In PDB	Homo sapiens (human)	Ubiquitin

Sequence modifications

A, B, C, J, K, L: 1 - 147 (UniProt: P62837)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag
Ser 85	Cys 85	conflict

A, B, C, J, K, L: 1025 - 1271 (UniProt: Q96FW1)

PDB	External Database	Details
Gly 148	-	linker
Gly 149	-	linker
Ser 150	-	linker
Ser 1091	Cys 91	conflict

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	377617.2
All*	Total formula weight	377617.2

*Water molecules are not included.