4JGH

Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5

Summary for 4JGH

DescriptorSuppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1, ... (4 entities in total)
Functional Keywordscullin-ring e3 ubiquitin ligases, ubiquitination, cytosol, ligase
Biological sourceHomo sapiens (human)
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Cellular locationNucleus (Probable) P62869 P83940
Total number of polymer chains4
Total molecular weight87878.48
Authors
Kim, Y.K.,Kwak, M.J.,Ku, B.,Suh, H.Y.,Joo, K.,Lee, J.,Jung, J.U.,Oh, B.H. (deposition date: 2013-03-01, release date: 2013-08-07)
Primary citation
Kim, Y.K.,Kwak, M.J.,Ku, B.,Suh, H.Y.,Joo, K.,Lee, J.,Jung, J.U.,Oh, B.H.
Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
Acta Crystallogr.,Sect.D, 69:1587-1597, 2013
PubMed: 23897481 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444913011220
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25022 1.3% 5.1%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171588
PDB entries from 2020-11-25