5IFR
Structure of the stable UBE2D3-UbDha conjugate
Summary for 5IFR
Entry DOI | 10.2210/pdb5ifr/pdb |
Descriptor | Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B, GLYCEROL, ... (4 entities in total) |
Functional Keywords | ubiquitin conjugate, dehydroalanine, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 25669.35 |
Authors | Pruneda, J.N.,Mulder, M.P.C.,Witting, K.,Ovaa, H.,Komander, D. (deposition date: 2016-02-26, release date: 2016-05-11, Last modification date: 2024-01-10) |
Primary citation | Mulder, M.P.,Witting, K.,Berlin, I.,Pruneda, J.N.,Wu, K.P.,Chang, J.G.,Merkx, R.,Bialas, J.,Groettrup, M.,Vertegaal, A.C.,Schulman, B.A.,Komander, D.,Neefjes, J.,El Oualid, F.,Ovaa, H. A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes. Nat.Chem.Biol., 12:523-530, 2016 Cited by PubMed: 27182664DOI: 10.1038/nchembio.2084 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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