Solution Structure of the UbcH5c/Ub Non-covalent Complex

Summary for 2FUH

DescriptorUbiquitin-conjugating enzyme E2 D3, Ubiquitin (2 entities in total)
Functional Keywordsprotein-protein complex ubiquitin ubiquitin-conjugating enzyme, ligase
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Peripheral membrane protein P61077
Total number of polymer chains2
Total molecular weight25151.77
Brzovic, P.S.,Lissounov, A.,Hoyt, D.W.,Klevit, R.E. (deposition date: 2006-01-26, release date: 2006-03-28, Last modification date: 2011-07-13)
Primary citation
Brzovic, P.S.,Lissounov, A.,Christensen, D.E.,Hoyt, D.W.,Klevit, R.E.
A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination.
Mol.Cell, 21:873-880, 2006
PubMed: 16543155 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2006.02.008
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers193.4%9.8%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report