6AZ1

Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin

Summary for 6AZ1

Entry DOI	10.2210/pdb6az1/pdb
Related	6AZ3
EMDB information	7024 7025
Descriptor	Ribosomal protein s1e, ribosomal protein S8, ribosomal protein S8e, ... (41 entities in total)
Functional Keywords	leishmania donovani, ribosome, aminoglycoside, paromomycin, ribosome-antibiotic complex, ribosome/antibiotic
Biological source	Leishmania donovani More
Total number of polymer chains	38
Total formula weight	1416658.06
Authors	Shalev-Benami, M.,Zhang, Y.,Rozenberg, H.,Matzov, D.,Zimmerman, E.,Bashan, A.,Jaffe, C.L.,Yonath, A.,Skiniotis, G. (deposition date: 2017-09-09, release date: 2017-12-06, Last modification date: 2019-07-03)
Primary citation	Shalev-Benami, M.,Zhang, Y.,Rozenberg, H.,Nobe, Y.,Taoka, M.,Matzov, D.,Zimmerman, E.,Bashan, A.,Isobe, T.,Jaffe, C.L.,Yonath, A.,Skiniotis, G. Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin. Nat Commun, 8:1589-1589, 2017 Cited by PubMed: 29150609 DOI: 10.1038/s41467-017-01664-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation