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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6AZ1

Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARibosomal protein s1epolymer26430092.11UniProt (E9BRS2)
Pfam (PF01015)
In PDB		Leishmania donovani
2Bribosomal protein S2polymer24627564.71Pfam (PF00318)
UniProt (by SIFTS) (A4IDS4)
In PDB		Leishmania donovani
3Cribosomal protein S3polymer21924511.81UniProt (E9BQ25)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Leishmania donovani
4Dribosomal protein S4polymer19022184.91UniProt (E9BTJ0)
Pfam (PF00163)
Pfam (PF01479)
UniProt (by SIFTS) (A0A3S5H5Z2)
In PDB		Leishmania donovani
5Eribosomal protein S4epolymer27330711.11UniProt (E9BBI6)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Pfam (PF08071)
Pfam (PF01479)
UniProt (by SIFTS) (A0A3Q8I8K3)
In PDB		Leishmania donovani
6Fribosomal protein S5polymer26528803.21UniProt (E9BNF0)
Pfam (PF00333)
Pfam (PF03719)
UniProt (by SIFTS) (A0A3S7X558)
In PDB		Leishmania donovani
7Gribosomal protein S6epolymer24928341.21Pfam (PF01092)
UniProt (by SIFTS) (O44012)
In PDB		Leishmania donovani
8Hribosomal protein S7polymer19021311.61Pfam (PF00177)
UniProt (by SIFTS) (A0A381MCG8)
In PDB		Leishmania donovani
9Iribosomal protein S7epolymer20023867.31UniProt (E9B7A8)
Pfam (PF01251)
UniProt (by SIFTS) (A0A3S7WNJ7)
In PDB		Leishmania donovani
10Jribosomal protein S8polymer13014719.31UniProt (E9BAV6)
Pfam (PF00410)
In PDB		Leishmania donovani
11Kribosomal protein S8epolymer22025038.31UniProt (E9BH78)
Pfam (PF01201)
UniProt (by SIFTS) (A0A3Q8ID68)
In PDB		Leishmania donovani
12Lribosomal protein S9polymer14916718.61UniProt (E9BI96)
Pfam (PF00380)
In PDB		Leishmania donovani
13Mribosomal protein S10polymer11613049.11Pfam (PF00338)
UniProt (by SIFTS) (E9BJI2)
In PDB		Leishmania donovani
14Nribosomal protein S10epolymer15317432.91UniProt (E9BTG4)
Pfam (PF03501)
In PDB		Leishmania donovani
15Oribosomal protein S11polymer14415609.11UniProt (E9BMA8)
Pfam (PF00411)
UniProt (by SIFTS) (A0A3S7X3Z7)
In PDB		Leishmania donovani
16Pribosomal protein S12polymer14315952.71UniProt (E9BFB6)
Pfam (PF00164)
In PDB		Leishmania donovani
17Qribosomal protein S12epolymer14115611.81UniProt (E9BBC0)
Pfam (PF01248)
UniProt (by SIFTS) (A0A3S5H6N5)
In PDB		Leishmania donovani
18Rribosomal protein S13polymer15317443.41UniProt (E9BTF9)
Pfam (PF00416)
In PDB		Leishmania donovani
19Sribosomal protein S14polymer576696.91UniProt (E9BJV7)
Pfam (PF00253)
In PDB		Leishmania donovani
20Tribosomal protein S15polymer15117455.71UniProt (E9BPR7)
Pfam (PF08069)
Pfam (PF00312)
UniProt (by SIFTS) (A0A3S7X790)
In PDB		Leishmania donovani
21Uribosomal protein S17polymer17319985.41Pfam (PF16205)
Pfam (PF00366)
UniProt (by SIFTS) (Q9TXA6)
In PDB		Leishmania donovani
22Vribosomal protein S17epolymer14316521.51UniProt (E9BJZ5)
Pfam (PF00833)
In PDB		Leishmania donovani
23Wribosomal protein S19polymer15217528.51Pfam (PF00203)
UniProt (by SIFTS) (E9BFQ0)
In PDB		Leishmania donovani
24Xribosomal protein S19epolymer17920188.61UniProt (E9BR60)
Pfam (PF01090)
In PDB		Leishmania donovani
25Yribosomal protein S21epolymer15916669.11Pfam (PF01249)
UniProt (by SIFTS) (E9BAR6)
In PDB		Leishmania donovani
26Zribosomal protein S24epolymer13715808.91UniProt (E9BU11)
Pfam (PF01282)
UniProt (by SIFTS) (A0A3Q8IKW0)
In PDB		Leishmania donovani
27aribosomal protein S25epolymer12013071.41UniProt (E9BHM6)
Pfam (PF03297)
In PDB		Leishmania donovani
28bribosomal protein S26epolymer11212794.31UniProt (E9BK95)
Pfam (PF01283)
In PDB		Leishmania donovani
29cribosomal protein S27epolymer869819.51UniProt (E9BUA2)
Pfam (PF01667)
UniProt (by SIFTS) (A0A3Q8ID11)
In PDB		Leishmania donovani
30dribosomal protein S28epolymer879763.21UniProt (E9BIH3)
Pfam (PF01200)
In PDB		Leishmania donovani
31eribosomal protein S30epolymer667394.91UniProt (E9BLG3)
Pfam (PF04758)
In PDB		Leishmania donovani
32fribosomal protein S31epolymer15217015.71UniProt (E9BTC5)
Pfam (PF00240)
Pfam (PF01599)
UniProt (by SIFTS) (A0A3S7XAC2)
In PDB		Leishmania donovani
33gLACK1polymer31234459.51UniProt (Q9BIJ5)
Pfam (PF00400)
In PDB		Leishmania donovani
341ribosomal RNA 18Spolymer2203710287.41GenBank (322500086)Leishmania donovani
352tRNA-Phepolymer7624599.71GenBank (1229082179)Escherichia coli
363P-site tRNApolymer7724786.81GenBank (817573384)Escherichia coli
374E-site tRNApolymer7624485.51GenBank (1229082179)Escherichia coli
385mRNApolymer134085.51Leishmania donovani
391, C, D, S, 5MAGNESIUM IONnon-polymer24.324Chemie (MG)
401PAROMOMYCINnon-polymer615.66Chemie (PAR)
41waterwater18.0262Chemie (HOH)
Sequence modifications
A: 0 - 263 (UniProt: E9BRS2)
PDBExternal DatabaseDetails
Ser 15Gly 16conflict
F: 1 - 265 (UniProt: E9BNF0)
PDBExternal DatabaseDetails
Thr 4Ala 4conflict
Gln 8-insertion
Ala 10Asn 9conflict
Ala 12Gly 11conflict
Ala 13Val 12conflict
Asp 14Glu 13conflict
Val 15Ala 14conflict
P: 1 - 143 (UniProt: E9BFB6)
PDBExternal DatabaseDetails
Arg 18Cys 18conflict
Ala 34Ser 34conflict
Lys 36Arg 36conflict
Ser 127Asn 127conflict
f: 1 - 152 (UniProt: E9BTC5)
PDBExternal DatabaseDetails
Ile 5Val 5conflict
1: 1 - 2203 (GenBank: 322500086)
PDBExternal DatabaseDetails
M1y 1539U 1020612conflict
C4j 1543U 1020608conflict
2: 4 - 76 (GenBank: 1229082179)
PDBExternal DatabaseDetails
G 1-expression tag
C 2-expression tag
G 3-expression tag
C 70G 899645conflict
4: 4 - 76 (GenBank: 1229082179)
PDBExternal DatabaseDetails
G 1-expression tag
C 2-expression tag
G 3-expression tag
C 70G 899645conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains38
Total formula weight1412381.0
Non-Polymers*Number of molecules30
Total formula weight4277.1
All*Total formula weight1416658.1
*Water molecules are not included.

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PDB entries from 2024-07-10

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