7PHR
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![BU of 7phr by Molmil](/molmil-images/mine/7phr) | Structure of a fully assembled T-cell receptor engaging a tumor-associated peptide-MHC I | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Susac, L, Thomas, C, Tampe, R. | 登録日 | 2021-08-18 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC. Cell, 185, 2022
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4L29
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![BU of 4l29 by Molmil](/molmil-images/mine/4l29) | Structure of wtMHC class I with NY-ESO1 double mutant | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | 著者 | Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S. | 登録日 | 2013-06-04 | 公開日 | 2013-12-25 | 最終更新日 | 2014-02-26 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin. J.Biol.Chem., 289, 2014
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3VWJ
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![BU of 3vwj by Molmil](/molmil-images/mine/3vwj) | Ternary crystal structure of the human NKT TCR-CD1d-C20:2 complex | 分子名称: | (11Z,14E)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | 著者 | Wun, K.S, Rossjohn, J. | 登録日 | 2012-08-24 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.093 Å) | 主引用文献 | Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex J.Biol.Chem., 287, 2012
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4WWK
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![BU of 4wwk by Molmil](/molmil-images/mine/4wwk) | Crystal structure of human TCR Alpha Chain-TRAV12-3, Beta Chain-TRBV6-5, Antigen-presenting molecule CD1d, and Beta-2-microglobulin | 分子名称: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | 著者 | Le Nours, J, Praveena, T, Pellicci, D.G, Gherardin, N.A, Lim, R.T, Besra, G, Keshipeddy, A, Richardson, S.K, Howell, A.R, Gras, S, Godfrey, D.I, Rossjohn, J, Uldrich, A.P. | 登録日 | 2014-11-11 | 公開日 | 2016-02-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens. Nat Commun, 7, 2016
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5W1W
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![BU of 5w1w by Molmil](/molmil-images/mine/5w1w) | Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex | 分子名称: | Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ... | 著者 | Gras, S, Walpole, N, Farenc, C, Rossjohn, J. | 登録日 | 2017-06-05 | 公開日 | 2017-10-04 | 最終更新日 | 2018-01-03 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors. J. Biol. Chem., 292, 2017
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1KTL
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![BU of 1ktl by Molmil](/molmil-images/mine/1ktl) | The human non-classical major histocompatibility complex molecule HLA-E | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... | 著者 | Holmes, M.A, Strong, R.K. | 登録日 | 2002-01-16 | 公開日 | 2003-02-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities J.Biol.Chem., 278, 2003
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7TUE
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![BU of 7tue by Molmil](/molmil-images/mine/7tue) | Crystal structure of Tapasin in complex with HLA-B*44:05 (T73C) | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B alpha chain, ... | 著者 | Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H. | 登録日 | 2022-02-02 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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3SJV
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![BU of 3sjv by Molmil](/molmil-images/mine/3sjv) | Crystal structure of the RL42 TCR in complex with HLA-B8-FLR | 分子名称: | Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J. | 登録日 | 2011-06-22 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. J.Immunol., 188, 2012
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1C16
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![BU of 1c16 by Molmil](/molmil-images/mine/1c16) | CRYSTAL STRUCTURE ANALYSIS OF THE GAMMA/DELTA T CELL LIGAND T22 | 分子名称: | MHC-LIKE PROTEIN T22, PROTEIN (BETA-2-MICROGLOBULIN) | 著者 | Wingren, C, Crowley, M.P, Degano, M, Chien, Y, Wilson, I.A. | 登録日 | 1999-07-20 | 公開日 | 2000-01-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structure of a gammadelta T cell receptor ligand T22: a truncated MHC-like fold. Science, 287, 2000
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6VMX
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![BU of 6vmx by Molmil](/molmil-images/mine/6vmx) | Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Farenc, C, Rossjohn, J, Gras, S. | 登録日 | 2020-01-28 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals. J Immunol., 205, 2020
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1UQS
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![BU of 1uqs by Molmil](/molmil-images/mine/1uqs) | The Crystal Structure of Human CD1b with a Bound Bacterial Glycolipid | 分子名称: | BETA-2-MICROGLOBULIN, GLUCOSE MONOMYCOLATE, T-CELL SURFACE GLYCOPROTEIN CD1B | 著者 | Batuwangala, T, Shepherd, D, Gadola, S.D, Gibson, K.J.C, Zaccai, N.R, Besra, G.S, Cerundolo, V, Jones, E.Y. | 登録日 | 2003-10-16 | 公開日 | 2003-10-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The crystal structure of human CD1b with a bound bacterial glycolipid. J Immunol., 172, 2004
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3KXF
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![BU of 3kxf by Molmil](/molmil-images/mine/3kxf) | Crystal Structure of SB27 TCR in complex with the 'restriction triad' mutant HLA-B*3508-13mer | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | 著者 | Archbold, J.K, Tynan, F.E, Gras, S, Rossjohn, J. | 登録日 | 2009-12-03 | 公開日 | 2010-06-09 | 最終更新日 | 2014-02-26 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability Proc.Natl.Acad.Sci.USA, 107, 2010
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3M1B
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![BU of 3m1b by Molmil](/molmil-images/mine/3m1b) | Crystal structure of human FcRn with a dimeric peptide inhibitor | 分子名称: | Beta-2-microglobulin, DIMERIC PEPTIDE INHIBITOR, IgG receptor FcRn large subunit p51 | 著者 | Mezo, A.R, Sridhar, V, Badger, J, Sakorafas, P, Nienaber, V. | 登録日 | 2010-03-04 | 公開日 | 2010-06-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn. J.Biol.Chem., 285, 2010
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3W39
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![BU of 3w39 by Molmil](/molmil-images/mine/3w39) | Crystal structure of HLA-B*5201 in complexed with HIV immunodominant epitope (TAFTIPSI) | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-52 alpha chain, ... | 著者 | Yagita, Y, Kuse, N, Kuroki, K, Gatanaga, H, Carlson, J.M, Chikata, T, Brumme, Z.L, Murakoshi, H, Akahoshi, T, Pfeifer, N, Mallal, S, John, M, Ose, T, Matsubara, H, Kanda, R, Fukunaga, Y, Honda, K, Kawashima, Y, Ariumi, Y, Oka, S, Maenaka, K, Takiguchi, M. | 登録日 | 2012-12-13 | 公開日 | 2013-02-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity J.Virol., 87, 2013
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7L1D
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![BU of 7l1d by Molmil](/molmil-images/mine/7l1d) | |
6RP9
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![BU of 6rp9 by Molmil](/molmil-images/mine/6rp9) | Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV | 分子名称: | Beta-2-microglobulin, Cancer/testis antigen 1, HLA class I histocompatibility antigen, ... | 著者 | Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. | 登録日 | 2019-05-14 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex. J Immunol., 204, 2020
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8VRA
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![BU of 8vra by Molmil](/molmil-images/mine/8vra) | Structure of a synthetic antibody in complex with a class I MHC presenting a hapten-peptide conjugate | 分子名称: | AMG 510 (bound form), Beta-2-microglobulin, GTPase KRas, ... | 著者 | Maso, L, Bang, I, Koide, S. | 登録日 | 2024-01-20 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Molecular basis for antibody recognition of multiple drug-peptide/MHC complexes. Proc.Natl.Acad.Sci.USA, 121, 2024
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3SDX
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![BU of 3sdx by Molmil](/molmil-images/mine/3sdx) | Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide | 分子名称: | Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, N-[(2S,3R)-1-(beta-D-galactopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]tetracosanamide, ... | 著者 | Clarke, A.J, Patel, O, Rossjohn, J. | 登録日 | 2011-06-09 | 公開日 | 2011-10-05 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors Nat.Immunol., 12, 2011
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6UK2
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![BU of 6uk2 by Molmil](/molmil-images/mine/6uk2) | |
7STF
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![BU of 7stf by Molmil](/molmil-images/mine/7stf) | Structure of KRAS G12V/HLA-A*03:01 in complex with antibody fragment V2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... | 著者 | Wright, K.M, Gabelli, S.B, Miller, M. | 登録日 | 2021-11-12 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nat Commun, 14, 2023
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6UZ1
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6K60
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![BU of 6k60 by Molmil](/molmil-images/mine/6k60) | Structural and functional basis for HLA-G isoform recognition of immune checkpoint receptor LILRBs | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain G, ... | 著者 | Kuroki, K, Matsubara, H, Kanda, R, Miyashita, N, Shiroishi, M, Fukunaga, Y, Kamishikiryo, J, Fukunaga, A, Hirose, K, Sugita, Y, Kita, S, Ose, T, Maenaka, K. | 登録日 | 2019-05-31 | 公開日 | 2019-11-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.149 Å) | 主引用文献 | Structural and Functional Basis for LILRB Immune Checkpoint Receptor Recognition of HLA-G Isoforms. J Immunol., 203, 2019
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7LLJ
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![BU of 7llj by Molmil](/molmil-images/mine/7llj) | Inhibitory immune receptor protein complex | 分子名称: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide, ... | 著者 | Rice, M.T, Littler, D.R, Rossjohn, J, Gully, B.S. | 登録日 | 2021-02-04 | 公開日 | 2021-11-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Recognition of the antigen-presenting molecule MR1 by a V delta 3 + gamma delta T cell receptor. Proc.Natl.Acad.Sci.USA, 118, 2021
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5WJL
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6EQA
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![BU of 6eqa by Molmil](/molmil-images/mine/6eqa) | HLA class I histocompatibility antigen | 分子名称: | ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Rizkallah, P.J, Cole, D.K. | 登録日 | 2017-10-12 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | TCR-induced alteration of primary MHC peptide anchor residue. Eur.J.Immunol., 49, 2019
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