6K60

Structural and functional basis for HLA-G isoform recognition of immune checkpoint receptor LILRBs

Summary for 6K60

• Entry DOI: 10.2210/pdb6k60/pdb
• Descriptor: HLA class I histocompatibility antigen, alpha chain G, Beta-2-microglobulin, Peptide from Histone H2A.J, ... (5 entities in total)
• Functional Keywords: hla class i, hlag, lilrb1/ilt2, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 135365.46

Authors

Kuroki, K.,Matsubara, H.,Kanda, R.,Miyashita, N.,Shiroishi, M.,Fukunaga, Y.,Kamishikiryo, J.,Fukunaga, A.,Hirose, K.,Sugita, Y.,Kita, S.,Ose, T.,Maenaka, K. (deposition date: 2019-05-31, release date: 2019-11-27, Last modification date: 2023-11-22)

• Primary citation: Kuroki, K.,Matsubara, H.,Kanda, R.,Miyashita, N.,Shiroishi, M.,Fukunaga, Y.,Kamishikiryo, J.,Fukunaga, A.,Fukuhara, H.,Hirose, K.,Hunt, J.S.,Sugita, Y.,Kita, S.,Ose, T.,Maenaka, K.; Structural and Functional Basis for LILRB Immune Checkpoint Receptor Recognition of HLA-G Isoforms.; J Immunol., 203:3386-3394, 2019; PubMed: 31694909; DOI: 10.4049/jimmunol.1900562

Experimental method

X-RAY DIFFRACTION (3.149 Å)