6K60
Structural and functional basis for HLA-G isoform recognition of immune checkpoint receptor LILRBs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | HLA class I histocompatibility antigen, alpha chain G | polymer | 277 | 32017.5 | 2 | UniProt (P17693) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | HLA G antigen,MHC class I antigen G |
| 2 | B, F (B, F) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C, G (C, G) | Peptide from Histone H2A.J | polymer | 9 | 1148.4 | 2 | UniProt (A0A0U1RRH7) UniProt (by SIFTS) (Q9BTM1) | Homo sapiens | |
| 4 | D, H (D, H) | Leukocyte immunoglobulin-like receptor subfamily B member 1 | polymer | 198 | 22129.8 | 2 | UniProt (A0A0G2JQ44) Pfam (PF13895) UniProt (by SIFTS) (Q8NHL6) | Homo sapiens (Human) | |
| 5 | I, J, K, L, M... (A, B, C, E, G) | IODIDE ION | non-polymer | 126.9 | 8 | Chemie (IOD) |
Sequence modifications
A, E: 1 - 276 (UniProt: P17693)
B, F: 1 - 99 (UniProt: P61769)
D, H: 1 - 197 (UniProt: A0A0G2JQ44)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 42 | Cys 66 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 134350.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1015.2 | |
| All* | Total formula weight | 135365.5 |
