6VMX
Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope
Summary for 6VMX
Entry DOI | 10.2210/pdb6vmx/pdb |
Descriptor | HLA class I histocompatibility antigen, B-7 alpha chain, Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, ... (8 entities in total) |
Functional Keywords | tcr, mhc, ebv, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 191264.67 |
Authors | Farenc, C.,Rossjohn, J.,Gras, S. (deposition date: 2020-01-28, release date: 2020-07-29, Last modification date: 2023-10-11) |
Primary citation | Rowntree, L.C.,Nguyen, T.H.O.,Farenc, C.,Halim, H.,Hensen, L.,Rossjohn, J.,Kotsimbos, T.C.,Purcell, A.W.,Kedzierska, K.,Gras, S.,Mifsud, N.A. A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals. J Immunol., 205:1524-1534, 2020 Cited by PubMed: 32817371DOI: 10.4049/jimmunol.2000249 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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