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3W39

Crystal structure of HLA-B*5201 in complexed with HIV immunodominant epitope (TAFTIPSI)

Summary for 3W39
Entry DOI10.2210/pdb3w39/pdb
DescriptorHLA class I histocompatibility antigen, B-52 alpha chain, Beta-2-microglobulin, peptid from Gag-Pol polyprotein (3 entities in total)
Functional Keywordsclass i major histocompatibility complex, mhc, membrane, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P30490
Secreted: P61769
Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12499
Total number of polymer chains6
Total formula weight89731.51
Authors
Primary citationYagita, Y.,Kuse, N.,Kuroki, K.,Gatanaga, H.,Carlson, J.M.,Chikata, T.,Brumme, Z.L.,Murakoshi, H.,Akahoshi, T.,Pfeifer, N.,Mallal, S.,John, M.,Ose, T.,Matsubara, H.,Kanda, R.,Fukunaga, Y.,Honda, K.,Kawashima, Y.,Ariumi, Y.,Oka, S.,Maenaka, K.,Takiguchi, M.
Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity
J.Virol., 87:2253-2263, 2013
Cited by
PubMed: 23236061
DOI: 10.1128/JVI.02572-12
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

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