3SDX

Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide

Summary for 3SDX

• Entry DOI: 10.2210/pdb3sdx/pdb
• Related: 3SCM 3SDA 3SDC 3SDD
• Descriptor: Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, NKT TCR Valpha24 chain, ... (6 entities in total)
• Functional Keywords: cd1d, autoimmunity, self-recognition, nkt, extracellular, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Single-pass type I membrane protein: P15813; Secreted: P61769
• Total number of polymer chains: 8
• Total formula weight: 189339.86

Authors

Clarke, A.J.,Patel, O.,Rossjohn, J. (deposition date: 2011-06-09, release date: 2011-10-05)

• Primary citation: Pellicci, D.G.,Clarke, A.J.,Patel, O.,Mallevaey, T.,Beddoe, T.,Le Nours, J.,Uldrich, A.P.,McCluskey, J.,Besra, G.S.,Porcelli, S.A.,Gapin, L.,Godfrey, D.I.,Rossjohn, J.; Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors; Nat.Immunol., 12:827-833, 2011; PubMed: 21804559; DOI: 10.1038/ni.2076

Experimental method

X-RAY DIFFRACTION (3.12 Å)