3SDX
Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, C) | Antigen-presenting glycoprotein CD1d | polymer | 275 | 31344.3 | 2 | UniProt (P15813) Pfam (PF16497) Pfam (PF07654) | Homo sapiens (human) | R3G1 |
| 2 | B, G (B, D) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | C, E (E, G) | NKT TCR Valpha24 chain | polymer | 204 | 22664.0 | 2 | Pfam (PF09291) UniProt (by SIFTS) (P01848) | Homo sapiens (human) | |
| 4 | D, H (F, H) | NKT TCR autoreactive-Vbeta11 chain | polymer | 247 | 28101.2 | 2 | Homo sapiens (human) | ||
| 5 | I, J (A, C) | N-[(2S,3R)-1-(beta-D-galactopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]tetracosanamide | non-polymer | 812.3 | 2 | Chemie (GCY) | |||
| 6 | K, L, M, N, O... (A, B, E, F, G...) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, C: 6 - 277 (UniProt: P15813)
| PDB | External Database | Details |
|---|---|---|
| His 278 | - | expression tag |
| His 279 | - | expression tag |
| His 280 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 187715.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1624.5 | |
| All* | Total formula weight | 189339.9 |
