3SDX
Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, C) | Antigen-presenting glycoprotein CD1d | polymer | 275 | 31344.3 | 2 | UniProt (P15813) Pfam (PF16497) Pfam (PF07654) | Homo sapiens (human) | R3G1 |
| 2 | B, G (B, D) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | C, E (E, G) | NKT TCR Valpha24 chain | polymer | 204 | 22664.0 | 2 | Pfam (PF09291) UniProt (by SIFTS) (P01848) | Homo sapiens (human) | |
| 4 | D, H (F, H) | NKT TCR autoreactive-Vbeta11 chain | polymer | 247 | 28101.2 | 2 | Homo sapiens (human) | ||
| 5 | I, J (A, C) | N-[(2S,3R)-1-(beta-D-galactopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]tetracosanamide | non-polymer | 812.3 | 2 | Chemie (GCY) PubChem (472745) PubChem (6475228) PubChem (44204804) PubChem (44260152) PubChem (44204805) PubChem (53477677) PubChem (176801639) PubChem (177532196) PubChem (74950937) PubChem (86289241) PubChem (101613910) PubChem (101417849) PubChem (5319015) PubChem (6321361) PubChem (6452860) PubChem (12304803) PubChem (163032025) PubChem (176048518) PubChem (86290162) PubChem (101281325) PubChem (101629418) PubChem (134758759) PubChem (163032022) PubChem (163032023) PubChem (163032024) | |||
| 6 | K, L, M, N, O... (A, B, E, F, G...) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, C: 6 - 277 (UniProt: P15813)
| PDB | External Database | Details |
|---|---|---|
| His 278 | - | expression tag |
| His 279 | - | expression tag |
| His 280 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 187715.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1624.5 | |
| All* | Total formula weight | 189339.9 |
