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PDB: 534 件

4KSL
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BU of 4ksl by Molmil
Gumby/Fam105B in complex with linear di-ubiquitin
分子名称: Polyubiquitin-C, Protein FAM105B
著者Juang, Y.-C, Ceccarelli, D.F, Sicheri, F.
登録日2013-05-17
公開日2013-06-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
5ZQ7
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BU of 5zq7 by Molmil
SidE-Ubi-NAD
分子名称: ADENOSINE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SidE, ...
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.847 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5E6J
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BU of 5e6j by Molmil
Structure of SARS PLpro bound to a Lys48-linked di-ubiquitin activity based probe
分子名称: ACETATE ION, NICKEL (II) ION, Polyubiquitin-B, ...
著者Lima, C.D, Bekes, M.
登録日2015-10-09
公開日2016-05-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.
Mol. Cell, 62, 2016
8EHO
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BU of 8eho by Molmil
PRRSV-1 PLP2 domain bound to ubiquitin
分子名称: 3-AMINOPROPANE, GLYCEROL, NITRATE ION, ...
著者Bailey-Elkin, B.A, Mark, B.L.
登録日2022-09-14
公開日2023-12-06
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis.
Plos Pathog., 19, 2023
4HXD
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BU of 4hxd by Molmil
Diversity of ubiquitin and ISG15 specificity amongst nairoviruses viral ovarian tumor domain proteases
分子名称: 1.7.6 3-bromanylpropan-1-amine, Polyubiquitin-C, RNA-directed RNA polymerase L, ...
著者Capodagli, G.C, Pegan, S.D.
登録日2012-11-09
公開日2013-02-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Diversity of Ubiquitin and ISG15 Specificity among Nairoviruses' Viral Ovarian Tumor Domain Proteases.
J.Virol., 87, 2013
8A9K
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BU of 8a9k by Molmil
Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 with ML323 (consensus reconstruction)
分子名称: 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, DNA (61-MER), Fanconi anemia group D2 protein, ...
著者Rennie, M.L, Walden, H.
登録日2022-06-28
公開日2022-10-12
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site.
Sci Adv, 8, 2022
5LRX
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BU of 5lrx by Molmil
Structure of A20 OTU domain bound to ubiquitin
分子名称: Polyubiquitin-B, Tumor necrosis factor alpha-induced protein 3
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
4JQW
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BU of 4jqw by Molmil
Crystal Structure of a Complex of NOD1 CARD and Ubiquitin
分子名称: Nucleotide-binding oligomerization domain-containing protein 1, PHOSPHATE ION, Polyubiquitin-C
著者Ver Heul, A.M, Gakhar, L, Piper, R.C, Ramaswamy, S.
登録日2013-03-20
公開日2014-03-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a complex of NOD1 CARD and ubiquitin
Plos One, 9, 2014
3ZLZ
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BU of 3zlz by Molmil
Lys6-linked tri-ubiquitin
分子名称: UBIQUITIN, ZINC ION
著者Hospenthal, M.K, Freund, S.M.V, Komander, D.
登録日2013-02-04
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Assembly, Analysis and Architecture of Atypical Ubiquitin Chains
Nat.Struct.Mol.Biol., 20, 2013
7KEO
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BU of 7keo by Molmil
Crystal structure of K29-linked di-ubiquitin in complex with synthetic antigen binding fragment
分子名称: PHOSPHATE ION, Synthetic antigen binding fragment, heavy chain, ...
著者Yu, Y, Zheng, Q, Erramilli, S, Pan, M, Kossiakoff, A, Liu, L, Zhao, M.
登録日2020-10-11
公開日2021-07-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.
Nat.Chem.Biol., 17, 2021
5JP3
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BU of 5jp3 by Molmil
Structure of Xanthomonas campestris effector protein XopD bound to ubiquitin
分子名称: Polyubiquitin-B, Xanthomonas outer protein D
著者Pruneda, J.N, Komander, D.
登録日2016-05-03
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
6CP2
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BU of 6cp2 by Molmil
SidC in complex with UbcH7~Ub
分子名称: Polyubiquitin-B, SidC, Ubiquitin-conjugating enzyme E2 L3
著者Wasilko, D.J, Huang, Q, Mao, Y.
登録日2018-03-13
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights into the ubiquitin transfer cascade catalyzed by theLegionellaeffector SidC.
Elife, 7, 2018
2ZVO
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BU of 2zvo by Molmil
NEMO CoZi domain in complex with diubiquitin in C2 space group
分子名称: NF-kappa-B essential modulator, UBC protein
著者Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I.
登録日2008-11-12
公開日2009-03-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
7EAO
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BU of 7eao by Molmil
The structure of the A20-binding inhibitor of NF-kB 1 in complex with tri-ubiquitin
分子名称: Polyubiquitin-C, TNFAIP3-interacting protein 1
著者Lo, Y.C, Lin, S.C.
登録日2021-03-07
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Biochemical Basis for Higher-Order Assembly between A20-Binding Inhibitor of NF-kappa B 1 (ABIN1) and M1-Linked Ubiquitins.
J.Mol.Biol., 433, 2021
6FYH
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BU of 6fyh by Molmil
Disulfide between ubiquitin G76C and the E3 HECT ligase Huwe1
分子名称: E3 ubiquitin-protein ligase HUWE1, Polyubiquitin-B, SULFATE ION, ...
著者Jaeckl, M, Hartmann, M.D, Wiesner, S.
登録日2018-03-12
公開日2018-07-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.
J. Mol. Biol., 430, 2018
4XOL
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BU of 4xol by Molmil
Observing the overall rocking motion of a protein in a crystal - Cubic Ubiquitin crystals.
分子名称: Ubiquitin, ZINC ION
著者Coquelle, N, Peixiang, M, Schanda, P, Colletier, J.P.
登録日2015-01-16
公開日2015-10-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Observing the overall rocking motion of a protein in a crystal.
Nat Commun, 6, 2015
8G6G
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BU of 8g6g by Molmil
H2BK120ub+H3K79me2-modified nucleosome ubiquitin position 5
分子名称: 601 DNA (185-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-02-15
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
7LYC
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BU of 7lyc by Molmil
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A Lys13 and Lys15 in complex with BARD1 (residues 415-777)
分子名称: BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G.
登録日2021-03-06
公開日2021-06-16
最終更新日2021-09-01
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Nature, 596, 2021
5OE7
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BU of 5oe7 by Molmil
Structure of OTULIN bound to the Met1-linked diubiquitin activity probe
分子名称: Polyubiquitin-C, Ubiquitin thioesterase otulin
著者Elliott, P.R, Komander, D.
登録日2017-07-07
公開日2017-09-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Cell Chem Biol, 24, 2017
8XEP
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BU of 8xep by Molmil
Crystal structure of a Legionella pneumophila type IV effector in complex with ubiquitin
分子名称: SULFATE ION, Type IV effector MavL, Ubiquitin
著者Tan, J.X, Wang, X.F, Zhou, Y, Zhu, Y.Q.
登録日2023-12-12
公開日2024-05-01
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling.
Nature, 2024
6NJ9
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BU of 6nj9 by Molmil
Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 2-to-1 complex
分子名称: 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ...
著者Worden, E.J, Hoffmann, N.A, Wolberger, C.
登録日2019-01-02
公開日2019-02-20
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
3EEC
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BU of 3eec by Molmil
X-ray structure of human ubiquitin Cd(II) adduct
分子名称: CADMIUM ION, Ubiquitin
著者Falini, G, Fermani, S, Tosi, G, Arnesano, F, Natile, G.
登録日2008-09-04
公開日2009-03-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural probing of Zn(II), Cd(II) and Hg(II) binding to human ubiquitin.
Chem.Commun.(Camb.), 45, 2008
8H1T
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BU of 8h1t by Molmil
Cryo-EM structure of BAP1-ASXL1 bound to chromatosome
分子名称: DNA (187-MER), Histone H1.4, Histone H2A type 1-D, ...
著者Ge, W, Yu, C, Xu, R.M.
登録日2022-10-04
公開日2023-02-01
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase.
Nature, 616, 2023
7MYF
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BU of 7myf by Molmil
Ubiquitin variant UbV.k.1 in complex with Ube2k
分子名称: Ubiquitin, Ubiquitin variant UbV.k.1, Ubiquitin-conjugating enzyme E2 K
著者Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S.
登録日2021-05-21
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.
Acs Chem.Biol., 16, 2021
5WQ4
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BU of 5wq4 by Molmil
Crystal structure of OPTN and linear diubiquitin complex
分子名称: Optineurin, ubiquitin
著者Li, F, Pan, L.
登録日2016-11-23
公開日2017-12-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Autophagy, 14, 2018

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