8H1T

Cryo-EM structure of BAP1-ASXL1 bound to chromatosome

Summary for 8H1T

• Entry DOI: 10.2210/pdb8h1t/pdb
• EMDB information: 34431 35179 35180 35181 35182
• Descriptor: Histone H3.1, Polycomb group protein ASXL1, Histone H4, ... (10 entities in total)
• Functional Keywords: nucleosome, histone deubiquitination, chromatin, gene regulation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 379323.15

Authors

Ge, W.,Yu, C.,Xu, R.M. (deposition date: 2022-10-04, release date: 2023-02-01, Last modification date: 2023-04-19)

• Primary citation: Ge, W.,Yu, C.,Li, J.,Yu, Z.,Li, X.,Zhang, Y.,Liu, C.P.,Li, Y.,Tian, C.,Zhang, X.,Li, G.,Zhu, B.,Xu, R.M.; Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase.; Nature, 616:176-182, 2023; PubMed: 36991118; DOI: 10.1038/s41586-023-05841-y

Experimental method

ELECTRON MICROSCOPY (3 Å)