8EHO

PRRSV-1 PLP2 domain bound to ubiquitin

Summary for 8EHO

• Entry DOI: 10.2210/pdb8eho/pdb
• Related: 8EHN
• Descriptor: Papain-like protease 2, Ubiquitin, ZINC ION, ... (7 entities in total)
• Functional Keywords: plp2, dub, deubiquitinating, viral protein
• Biological source: Porcine reproductive and respiratory syndrome virus (PRRSV); More
• Total number of polymer chains: 6
• Total formula weight: 92840.93

Authors

Bailey-Elkin, B.A.,Mark, B.L. (deposition date: 2022-09-14, release date: 2023-12-06, Last modification date: 2024-01-03)

• Primary citation: Bailey-Elkin, B.A.,Knaap, R.C.M.,De Silva, A.,Boekhoud, I.M.,Mous, S.,van Vught, N.,Khajehpour, M.,van den Born, E.,Kikkert, M.,Mark, B.L.; Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis.; Plos Pathog., 19:e1011872-e1011872, 2023; PubMed: 38096325; DOI: 10.1371/journal.ppat.1011872

Experimental method

X-RAY DIFFRACTION (2.85 Å)