8EHN

PRRSV-1 PLP2 domain

Summary for 8EHN

Entry DOI	10.2210/pdb8ehn/pdb
Descriptor	Papain-like protease 2, ZINC ION, ACETATE ION, ... (5 entities in total)
Functional Keywords	plp2, dub, deubiquitinating, viral protein
Biological source	Porcine reproductive and respiratory syndrome virus More
Total number of polymer chains	2
Total formula weight	44227.81
Authors	Bailey-Elkin, B.A.,Mark, B.L. (deposition date: 2022-09-14, release date: 2023-12-06, Last modification date: 2024-01-03)
Primary citation	Bailey-Elkin, B.A.,Knaap, R.C.M.,De Silva, A.,Boekhoud, I.M.,Mous, S.,van Vught, N.,Khajehpour, M.,van den Born, E.,Kikkert, M.,Mark, B.L. Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis. Plos Pathog., 19:e1011872-e1011872, 2023 Cited by PubMed: 38096325 DOI: 10.1371/journal.ppat.1011872 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation