6NJ9
Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 2-to-1 complex
Summary for 6NJ9
| Entry DOI | 10.2210/pdb6nj9/pdb |
| EMDB information | 9384 |
| Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (9 entities in total) |
| Functional Keywords | ubiquitin, nucleosome, methyltransferase, structural protein-transferase-dna complex, structural protein/transferase/dna |
| Biological source | Xenopus laevis (African clawed frog) More |
| Total number of polymer chains | 14 |
| Total formula weight | 311849.13 |
| Authors | Worden, E.J.,Hoffmann, N.A.,Wolberger, C. (deposition date: 2019-01-02, release date: 2019-02-20, Last modification date: 2021-06-16) |
| Primary citation | Worden, E.J.,Hoffmann, N.A.,Hicks, C.W.,Wolberger, C. Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L. Cell, 176:1490-1501.e12, 2019 Cited by PubMed: 30765112DOI: 10.1016/j.cell.2019.02.002 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.96 Å) |
Structure validation
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