4H5S
| Complex structure of Necl-2 and CRTAM | Descriptor: | Cell adhesion molecule 1, Cytotoxic and regulatory T-cell molecule | Authors: | Zhang, S, Lu, G, Qi, J, Li, Y, Zhang, Z, Zhang, B, Yan, J, Gao, G.F. | Deposit date: | 2012-09-18 | Release date: | 2013-08-07 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Competition of cell adhesion and immune recognition: insights into the interaction between CRTAM and nectin-like 2. Structure, 21, 2013
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6JJP
| Crystal structure of Fab of a PD-1 monoclonal antibody MW11-h317 in complex with PD-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of MW11-h317, Programmed cell death protein 1, ... | Authors: | Wang, M, Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M. | Deposit date: | 2019-02-26 | Release date: | 2019-10-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation. Commun Biol, 2, 2019
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6ISC
| complex structure of mCD226-ecto and hCD155-D1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD226 antigen, Poliovirus receptor | Authors: | Wang, H, Qi, J, Zhang, S, Li, Y, Tan, S, Gao, G.F. | Deposit date: | 2018-11-16 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding mode of the side-by-side two-IgV molecule CD226/DNAM-1 to its ligand CD155/Necl-5. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6K0Y
| Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor | Descriptor: | 1,2-ETHANEDIOL, Antibody Heavy Chain, Antibody Light Chain, ... | Authors: | Liu, J.X, Wang, G.Q. | Deposit date: | 2019-05-08 | Release date: | 2019-12-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor. Sci Rep, 9, 2019
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6IGO
| Crystal structure of myelin protein zero-like protein 1 (MPZL1) | Descriptor: | Myelin protein zero-like protein 1 | Authors: | Yu, T. | Deposit date: | 2018-09-25 | Release date: | 2018-11-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.746 Å) | Cite: | Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1 Biochem. Biophys. Res. Commun., 506, 2018
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4HZA
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6U6V
| Crystal structure of human PD-1H / VISTA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, V-type immunoglobulin domain-containing suppressor of T-cell activation | Authors: | Slater, B.T, Han, X, Chen, L, Xiong, Y. | Deposit date: | 2019-08-30 | Release date: | 2020-01-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insight into T cell coinhibition by PD-1H (VISTA). Proc.Natl.Acad.Sci.USA, 117, 2020
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6TXZ
| FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3 | Descriptor: | Fab H, Fab L, Hepatitis A virus cellular receptor 2 | Authors: | Musil, D, Sood, V. | Deposit date: | 2020-01-15 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology, 9, 2020
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6UMV
| Human apo PD-1 double mutant | Descriptor: | CHLORIDE ION, Programmed cell death protein 1 | Authors: | Tang, S, Kim, P.S. | Deposit date: | 2019-10-10 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.424 Å) | Cite: | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery. Proc.Natl.Acad.Sci.USA, 116, 2019
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1WTL
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1Z9M
| Crystal Structure of Nectin-like molecule-1 protein Domain 1 | Descriptor: | GAPA225 | Authors: | Dong, X, Xu, F, Gong, Y, Gao, J, Lin, P, Chen, T, Peng, Y, Qiang, B, Yuan, J, Peng, X, Rao, Z. | Deposit date: | 2005-04-03 | Release date: | 2006-02-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the V Domain of Human Nectin-like Molecule-1/Syncam3/Tsll1/Igsf4b, a Neural Tissue-specific Immunoglobulin-like Cell-Cell Adhesion Molecule J.Biol.Chem., 281, 2006
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1ZOX
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1XT5
| Crystal Structure of VCBP3, domain 1, from Branchiostoma floridae | Descriptor: | SULFATE ION, variable region-containing chitin-binding protein 3 | Authors: | Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Allaire, M, Jakoncic, J, Stojanoff, V, Litman, G.W, Ostrov, D.A. | Deposit date: | 2004-10-21 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus. Nat.Immunol., 7, 2006
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1XED
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5GGS
| PD-1 in complex with pembrolizumab Fab | Descriptor: | Programmed cell death protein 1, heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGV
| CTLA-4 in complex with tremelimumab Fab | Descriptor: | Cytotoxic T-lymphocyte protein 4, heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGT
| PD-L1 in complex with BMS-936559 Fab | Descriptor: | IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1 | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGR
| PD-1 in complex with nivolumab Fab | Descriptor: | Programmed cell death protein 1, heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5HDO
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5IMO
| Nanobody targeting mouse Vsig4 in Spacegroup P3221 | Descriptor: | Nanobody, Protein Vsig4 | Authors: | Wen, Y, Zheng, F. | Deposit date: | 2016-03-06 | Release date: | 2017-01-11 | Last modified: | 2017-07-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
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5IR3
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5FDY
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5IMM
| Nanobody targeting mouse Vsig4 in Spacegroup P212121 | Descriptor: | Nanobody, Protein Vsig4 | Authors: | Wen, Y, Zheng, F. | Deposit date: | 2016-03-06 | Release date: | 2017-01-11 | Last modified: | 2017-07-05 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
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1TVD
| VARIABLE DOMAIN OF T CELL RECEPTOR DELTA CHAIN | Descriptor: | T CELL RECEPTOR | Authors: | Li, H.M, Lebedeva, M.I, Llera, A.S, Fields, B.A, Brenner, M.B, Mariuzza, R.A. | Deposit date: | 1997-10-19 | Release date: | 1998-04-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor. Nature, 391, 1998
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1U9K
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