5GGT
PD-L1 in complex with BMS-936559 Fab
Summary for 5GGT
Entry DOI | 10.2210/pdb5ggt/pdb |
Related | 5GGQ 5GGR 5GGS 5GGU 5GGV |
Descriptor | Programmed cell death 1 ligand 1, IgG H chain, IGK@ protein (3 entities in total) |
Functional Keywords | antibody, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Endomembrane system ; Single-pass type I membrane protein : Q9NZQ7 |
Total number of polymer chains | 3 |
Total formula weight | 61728.31 |
Authors | Heo, Y.S. (deposition date: 2016-06-16, release date: 2016-11-09, Last modification date: 2024-03-20) |
Primary citation | Lee, J.Y.,Lee, H.T.,Shin, W.,Chae, J.,Choi, J.,Kim, S.H.,Lim, H.,Won Heo, T.,Park, K.Y.,Lee, Y.J.,Ryu, S.E.,Son, J.Y.,Lee, J.U.,Heo, Y.S. Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7:13354-13354, 2016 Cited by PubMed: 27796306DOI: 10.1038/ncomms13354 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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