4GOS

Crystal structure of human B7-H4 IgV-like domain

Summary for 4GOS

Entry DOI	10.2210/pdb4gos/pdb
Descriptor	V-set domain-containing T-cell activation inhibitor 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	immunoglobulin domain, glycoprotein, disulfide bond, immunity, adaptive immunity, structural genomics, psi-biology, protein structure initiative, new york structural genomics research consortium, nysgrc, immunoglobulin variable-like domain, cell surface, immune system, atoms-to-animals: the immune function network, ifn
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	14633.26
Authors	Vigdorovich, V.,Ramagopal, U.,Bhosle, R.,Toro, R.,Nathenson, S.G.,Almo, S.C.,New York Structural Genomics Research Consortium (NYSGRC),Atoms-to-Animals: The Immune Function Network (IFN) (deposition date: 2012-08-20, release date: 2012-09-12, Last modification date: 2020-07-29)
Primary citation	Jeon, H.,Vigdorovich, V.,Garrett-Thomson, S.C.,Janakiram, M.,Ramagopal, U.A.,Abadi, Y.M.,Lee, J.S.,Scandiuzzi, L.,Ohaegbulam, K.C.,Chinai, J.M.,Zhao, R.,Yao, Y.,Mao, Y.,Sparano, J.A.,Almo, S.C.,Zang, X. Structure and cancer immunotherapy of the B7 family member B7x. Cell Rep, 9:1089-1098, 2014 Cited by PubMed: 25437562 DOI: 10.1016/j.celrep.2014.09.053 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation