4K55

Structure of the extracellular domain of butyrophilin BTN3A1 in complex with (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP)

Summary for 4K55

Entry DOI	10.2210/pdb4k55/pdb
Related	4jkw
Descriptor	Butyrophilin subfamily 3 member A1, (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate (3 entities in total)
Functional Keywords	immunoglobulin superfamily, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Single-pass type I membrane protein: O00481
Total number of polymer chains	1
Total formula weight	14034.61
Authors	Kumar, A.,Mori, L.,De Libero, G. (deposition date: 2013-04-13, release date: 2013-07-24, Last modification date: 2013-09-25)
Primary citation	Vavassori, S.,Kumar, A.,Wan, G.S.,Ramanjaneyulu, G.S.,Cavallari, M.,El Daker, S.,Beddoe, T.,Theodossis, A.,Williams, N.K.,Gostick, E.,Price, D.A.,Soudamini, D.U.,Voon, K.K.,Olivo, M.,Rossjohn, J.,Mori, L.,De Libero, G. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human gamma delta T cells. Nat.Immunol., 14:908-916, 2013 Cited by PubMed: 23872678 DOI: 10.1038/ni.2665 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation