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8ESB	CryoEM structure of HLA-A2 bound to MAGEA8 (232-241) peptide Descriptor: Beta-2-microglobulin,HLA class I antigen,MAGE-A8 peptide chimera Authors: Saotome, K, Franklin, M.C. Deposit date: 2022-10-13 Release date: 2023-05-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
8ESA	CryoEM structure of HLA-A2 bound to MAGEA4 (230-239) peptide Descriptor: Beta-2-microglobulin,HLA class I antigen,MAGE-A4 peptide chimera Authors: Saotome, K, Franklin, M.C. Deposit date: 2022-10-13 Release date: 2023-05-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
8ES9	CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... Authors: Saotome, K, Franklin, M.C. Deposit date: 2022-10-13 Release date: 2023-05-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
8ES8	CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... Authors: Saotome, K, Franklin, M.C. Deposit date: 2022-10-13 Release date: 2023-05-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
7Z50	Structure of the highly diabetogenic 4.1-T cell receptor targeting a hybrid insulin peptide bound to I-Ag7. Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4.1 TCR alpha chain, ... Authors: Lopez-Sagaseta, J, Erausquin, E. Deposit date: 2022-03-06 Release date: 2022-07-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural plasticity in I-A g7 links autoreactivity to hybrid insulin peptides in type I diabetes. Front Immunol, 13, 2022
3I6G	Newly identified epitope Mn2 from SARS-CoV M protein complexed withHLA-A*0201 Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... Authors: Liu, J. Deposit date: 2009-07-07 Release date: 2010-06-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.201 Å) Cite: The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes. J.INFECT.DIS., 202, 2010
3HLA	HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN A2.1 Descriptor: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2.1) (ALPHA CHAIN) Authors: Saper, M.A, Bjorkman, P.J, Wiley, D.C. Deposit date: 1989-10-06 Release date: 1990-04-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution. J.Mol.Biol., 219, 1991
8EK5	Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 Descriptor: 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... Authors: Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. Deposit date: 2022-09-20 Release date: 2023-12-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
7YX9	MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange Descriptor: 1,2-ETHANEDIOL, CLIP 103-107, HLA class II histocompatibility antigen, ... Authors: Roske, Y, Abualrous, E.T. Deposit date: 2022-02-15 Release date: 2023-02-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.76 Å) Cite: MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange. Nat.Chem.Biol., 19, 2023
7YXB	MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, CLIP peptide, ... Authors: Roske, Y, Abualrous, E.T, Freund, C. Deposit date: 2022-02-15 Release date: 2023-02-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.095 Å) Cite: MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange. Nat.Chem.Biol., 19, 2023
8EMG	Crystal structure of a HLA-B*35:01-NP7 epitope from 2002 H2N1 influenza strain Descriptor: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.83001268 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMF	Crystal structure of a HLA-B*35:01-NP6 epitope from 1977 H1N1 influenza strain Descriptor: Beta-2-microglobulin, MHC class I antigen, Nucleoprotein NP6 epitope Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.80482423 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMI	Crystal structure of a HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain Descriptor: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.57301509 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMJ	Crystal structure of HLA-B*35:01-NP9 epitope from 2006 H1N1 influenza strain Descriptor: Beta-2-microglobulin, MHC class I antigen, Nucleoprotein NP9 epitope Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.75002885 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8ENH	Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP7 epitope from 2002 H3N2 influenza strain Descriptor: 3180 TCR alpha chain, Beta-2-microglobulin, MHC class I antigen, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-30 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (2.500032 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EMK	Crystal structure of HLA-B*35:01-NP3 epitope from 1957 H2N2 influenza strain Descriptor: Beta-2-microglobulin, MHC class I antigen, Nucleoprotein NP3 epitope, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-27 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.66523 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8EN8	Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP4 epitope from 1972 influenza strain Descriptor: 3180 TCR alpha chain, 3180 TCR beta chain, Beta-2-microglobulin, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-09-29 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (2.700012 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
7Z0Q	MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange Descriptor: 1,2-ETHANEDIOL, CLIP peptide, HLA class II histocompatibility antigen, ... Authors: Roske, Y, Abualrous, E.T, Freund, C. Deposit date: 2022-02-23 Release date: 2023-03-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange. Nat.Chem.Biol., 19, 2023
8EO8	Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain Descriptor: 3180 alpha chain, 3180 beta chain, Beta-2-microglobulin, ... Authors: Littler, D.R, Rossjohn, J. Deposit date: 2022-10-02 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (2.300001 Å) Cite: Molecular determinants of cross-strain influenza A virus recognition by T-cell receptors To Be Published
8F7M	Crystal Structure of HLA-B*57:01-TW10-T242N complex Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... Authors: Chatzileontiadou, D.S.M, Lobos, C.A, Gras, S. Deposit date: 2022-11-18 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Crystal Structure of HLA-B*57:01-TW10-T242N complex To Be Published
8FHL	Structure of pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ... Authors: Custodio, J.M.F, Baker, B.M. Deposit date: 2022-12-14 Release date: 2023-06-28 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.194 Å) Cite: Structure of Pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd To Be Published
8FHU	Structure of Pyruvate dehydrogenase phosphatase regulatory subunit epitope presented by H2-Dd Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ... Authors: Custodio, J.M.F, Baker, B.M. Deposit date: 2022-12-15 Release date: 2023-06-28 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Structure of Pyruvate dehydrogenase phosphatase regulatory subunit neoepitope presented by H2-Dd To Be Published
3IU3	Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain Descriptor: Heavy chain of Fab fragment of Basiliximab, Interleukin-2 receptor alpha chain, Light chain of Fab fragment of Basiliximab, ... Authors: Du, J, Yang, H, Wang, J, Ding, J. Deposit date: 2009-08-29 Release date: 2010-01-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab J.Immunol., 184, 2010
7ZT2	Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU Descriptor: 1,2-ETHANEDIOL, 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, ... Authors: Karuppiah, V, Srikannathasan, V, Robinson, R.A. Deposit date: 2022-05-09 Release date: 2023-06-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
7ZT4	Structure of E8 TCR in complex with human MR1 bound to 6FP Descriptor: 2-azanyl-6-methyl-3~{H}-pteridin-4-one, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... Authors: Karuppiah, V, Robinson, R.A. Deposit date: 2022-05-09 Release date: 2023-06-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023

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