3I6G

Newly identified epitope Mn2 from SARS-CoV M protein complexed withHLA-A*0201

Summary for 3I6G

• Entry DOI: 10.2210/pdb3i6g/pdb
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Membrane protein, ... (4 entities in total)
• Functional Keywords: hla-a2, sars-cov, membrane glycoprotein, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, envelope protein, golgi apparatus, viral matrix protein, virion, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769; Virion membrane; Multi-pass membrane protein (Potential): P59596
• Total number of polymer chains: 6
• Total formula weight: 89697.81

Authors

Liu, J. (deposition date: 2009-07-07, release date: 2010-06-16, Last modification date: 2023-11-01)

• Primary citation: Liu, J.,Sun, Y.,Qi, J.,Chu, F.,Wu, H.,Gao, F.,Li, T.,Yan, J.,Gao, G.F.; The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes.; J.INFECT.DIS., 202:1171-1180, 2010; PubMed: 20831383; DOI: 10.1086/656315

Experimental method

X-RAY DIFFRACTION (2.201 Å)