8ES9
CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4
Summary for 8ES9
Entry DOI | 10.2210/pdb8es9/pdb |
EMDB information | 28570 28571 28572 28573 28574 |
Descriptor | PN45428 TCR alpha chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total) |
Functional Keywords | tcr, receptor, membrane protein, cd3, mhc, hla, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 11 |
Total formula weight | 240267.21 |
Authors | |
Primary citation | Saotome, K.,Dudgeon, D.,Colotti, K.,Moore, M.J.,Jones, J.,Zhou, Y.,Rafique, A.,Yancopoulos, G.D.,Murphy, A.J.,Lin, J.C.,Olson, W.C.,Franklin, M.C. Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM Nat Commun, 14:2401-, 2023 Cited by DOI: 10.1038/s41467-023-37532-7PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.25 Å) |
Structure validation
Download full validation report