7YX9
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange
Summary for 7YX9
Entry DOI | 10.2210/pdb7yx9/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen, CLIP 103-107, ... (5 entities in total) |
Functional Keywords | hla-dr, clip peptide, mhcii, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 97473.57 |
Authors | Roske, Y.,Abualrous, E.T. (deposition date: 2022-02-15, release date: 2023-02-22, Last modification date: 2024-02-07) |
Primary citation | Abualrous, E.T.,Stolzenberg, S.,Sticht, J.,Wieczorek, M.,Roske, Y.,Gunther, M.,Dahn, S.,Boesen, B.B.,Calvo, M.M.,Biese, C.,Kuppler, F.,Medina-Garcia, A.,Alvaro-Benito, M.,Hofer, T.,Noe, F.,Freund, C. MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange. Nat.Chem.Biol., 19:1196-1204, 2023 Cited by PubMed: 37142807DOI: 10.1038/s41589-023-01316-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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