7YX9
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | HLA class II histocompatibility antigen, DR alpha chain | polymer | 192 | 22207.1 | 2 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | MHC class II antigen DRA |
2 | B, D | MHC class II antigen | polymer | 217 | 24512.2 | 2 | UniProt (A0A4E9DJJ3) Pfam (PF00969) Pfam (PF07654) In PDB | Homo sapiens (human) | |
3 | E, G | CLIP 103-107 | polymer | 15 | 1676.1 | 2 | UniProt (by SIFTS) (P04233) In PDB | Homo sapiens (human) | |
4 | A, B, C, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
5 | water | water | 18.0 | 907 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 191 (UniProt: P01903)
B, D: 34 - 231 (UniProt: A0A4E9DJJ3)
PDB | External Database | Details |
---|---|---|
Val 192 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 16 | - | expression tag |
Asn 17 | - | expression tag |
Ser 18 | - | expression tag |
Gly 19 | - | expression tag |
Gly 20 | - | expression tag |
Gly 21 | - | expression tag |
Ser 22 | - | expression tag |
Leu 23 | - | expression tag |
Val 24 | - | expression tag |
Pro 25 | - | expression tag |
Arg 26 | - | expression tag |
Gly 27 | - | expression tag |
Ser 28 | - | expression tag |
Gly 29 | - | expression tag |
Gly 30 | - | expression tag |
Gly 31 | - | expression tag |
Gly 32 | - | expression tag |
Ser 33 | - | expression tag |
Val 232 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 96790.8 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 682.7 | |
All* | Total formula weight | 97473.6 |