7ZT2
Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU
Summary for 7ZT2
Entry DOI | 10.2210/pdb7zt2/pdb |
Descriptor | Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, E8 TCR Alpha, ... (7 entities in total) |
Functional Keywords | tcr, mr1, 5-op-ru, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 98230.35 |
Authors | Karuppiah, V.,Srikannathasan, V.,Robinson, R.A. (deposition date: 2022-05-09, release date: 2023-06-28, Last modification date: 2024-02-07) |
Primary citation | Chancellor, A.,Alan Simmons, R.,Khanolkar, R.C.,Nosi, V.,Beshirova, A.,Berloffa, G.,Colombo, R.,Karuppiah, V.,Pentier, J.M.,Tubb, V.,Ghadbane, H.,Suckling, R.J.,Page, K.,Crean, R.M.,Vacchini, A.,De Gregorio, C.,Schaefer, V.,Constantin, D.,Gligoris, T.,Lloyd, A.,Hock, M.,Srikannathasan, V.,Robinson, R.A.,Besra, G.S.,van der Kamp, M.W.,Mori, L.,Calogero, R.,Cole, D.K.,De Libero, G.,Lepore, M. Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220:-, 2023 Cited by PubMed: 37382893DOI: 10.1084/jem.20221939 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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