8ES8

CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239)

Summary for 8ES8

• Entry DOI: 10.2210/pdb8es8/pdb
• EMDB information: 28570 28571 28572 28573 28574
• Descriptor: T-cell surface glycoprotein CD3 zeta chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• Functional Keywords: tcr, membrane protein, cd3, hla, mhc, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 11
• Total formula weight: 242046.00

Authors

Saotome, K.,Franklin, M.C. (deposition date: 2022-10-13, release date: 2023-05-03)

• Primary citation: Saotome, K.,Dudgeon, D.,Colotti, K.,Moore, M.J.,Jones, J.,Zhou, Y.,Rafique, A.,Yancopoulos, G.D.,Murphy, A.J.,Lin, J.C.,Olson, W.C.,Franklin, M.C.; Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM; Nat Commun, 14:2401-, 2023; DOI: 10.1038/s41467-023-37532-7

Experimental method

ELECTRON MICROSCOPY (2.65 Å)