7D00
| S protein of SARS-CoV-2 in complex bound with FabP5A-1B8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IG c642_heavy_IGHV3-53_IGHD1-26_IGHJ6,chain H of FabP5A-1B8,IGH@ protein, ... | Authors: | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | Deposit date: | 2020-09-09 | Release date: | 2021-03-10 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies. Cell Res., 31, 2021
|
|
7D03
| S protein of SARS-CoV-2 in complex bound with FabP5A-2G7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IGL c2312_light_IGLV2-14_IGLJ2,IGL@ protein, ... | Authors: | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | Deposit date: | 2020-09-09 | Release date: | 2021-03-10 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies. Cell Res., 31, 2021
|
|
7B0B
| Fab HbnC3t1p1_C6 bound to SARS-CoV-2 RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, IGK@ protein, ... | Authors: | Borenstein-Katz, A, Diskin, R. | Deposit date: | 2020-11-19 | Release date: | 2021-12-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants. Immunity, 56, 2023
|
|
3B2U
| Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ... | Authors: | Ferguson, K.M, Li, S, Kussie, P. | Deposit date: | 2007-10-19 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8. Structure, 16, 2008
|
|
3B2V
| Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ... | Authors: | Ferguson, K.M, Li, S, Kussie, P. | Deposit date: | 2007-10-19 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8. Structure, 16, 2008
|
|
3BGF
| |
2ZNX
| 5-Fluorotryptophan Incorporated ScFv10 Complexed to Hen Egg Lysozyme | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Lysozyme C, ScFv | Authors: | DeSantis, M.E, Acchione, M, Li, M, Walter, R.L, Wlodawer, A, Smith-Gill, S. | Deposit date: | 2008-05-02 | Release date: | 2009-01-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics Biochemistry, 51, 2012
|
|
3BAE
| Crystal structure of Fab WO2 bound to the N terminal domain of Amyloid beta peptide (1-28) | Descriptor: | Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Parker, M.W. | Deposit date: | 2007-11-07 | Release date: | 2008-04-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.593 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
|
|
3BKC
| Crystal structure of anti-amyloid beta FAB WO2 (P21, FormB) | Descriptor: | SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | Deposit date: | 2007-12-06 | Release date: | 2008-04-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
|
|
3BQU
| Crystal Structure of the 2F5 Fab'-3H6 Fab Complex | Descriptor: | 2F5 Fab' heavy chain, 2F5 Fab' light chain, 3H6 Fab heavy chain, ... | Authors: | Bryson, S, Julien, J.-P, Isenman, D.E, Kunert, R, Katinger, H, Pai, E.F. | Deposit date: | 2007-12-20 | Release date: | 2008-10-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6. J.Mol.Biol., 382, 2008
|
|
3BN9
| Crystal Structure of MT-SP1 in complex with Fab Inhibitor E2 | Descriptor: | 1,2-ETHANEDIOL, E2 Fab Heavy Chain, E2 Fab Light Chain, ... | Authors: | Farady, C.J, Schneider, E.L, Egea, P.F, Goetz, D.H, Craik, C.S. | Deposit date: | 2007-12-13 | Release date: | 2008-09-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.173 Å) | Cite: | Structure of an Fab-protease complex reveals a highly specific non-canonical mechanism of inhibition J.Mol.Biol., 380, 2008
|
|
6UBI
| |
6UDJ
| HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074 | Descriptor: | 1-18 Fab Heavy Chain, 1-18 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | Authors: | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | Deposit date: | 2019-09-19 | Release date: | 2020-01-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180, 2020
|
|
6UDK
| HIV-1 bNAb 1-55 in complex with modified BG505 SOSIP-based immunogen RC1 and 10-1074 | Descriptor: | 1-55 Fab Heavy Chain, 1-55 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | Authors: | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | Deposit date: | 2019-09-19 | Release date: | 2020-01-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180, 2020
|
|
6U3I
| |
6UGU
| Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a C-centered orthorhombic crystal form, Lot C | Descriptor: | PF06438179 Fab Heavy Chain, PF06438179 Fab Light Chain | Authors: | Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D. | Deposit date: | 2019-09-26 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
|
|
6UC5
| Fab397 in complex with NPNA peptide | Descriptor: | Fab397 heavy chain, Fab397 light chain, NPNA peptide | Authors: | Pholcharee, T, Oyen, D, Wilson, I.A. | Deposit date: | 2019-09-13 | Release date: | 2020-01-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein. J.Mol.Biol., 432, 2020
|
|
6UGS
| Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A | Descriptor: | Infliximab (Remicade) Fab Heavy Chain, Infliximab (Remicade) Fab Light Chain | Authors: | Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H. | Deposit date: | 2019-09-26 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
|
|
6UMX
| Structural basis for specific inhibition of extracellular activation of pro/latent myostatin by SRK-015 | Descriptor: | GL29H4-16 Fab Heavy Chain,GL29H4-16 Fab Heavy Chain, GL29H4-16 Fab Light Chain,GL29H4-16 Fab Light Chain, GLYCEROL, ... | Authors: | Dagbay, K.B, Treece, E, Streich Jr, F.C, Jackson, J.W, Faucette, R.R, Nikiforov, A, Lin, S.C, Bostion, C.J, Nicholls, S.B, Capili, A.D, Carven, G.J. | Deposit date: | 2019-10-10 | Release date: | 2020-02-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015. J.Biol.Chem., 295, 2020
|
|
6U2F
| |
6U1N
| GPCR-Beta arrestin structure in lipid bilayer | Descriptor: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, Beta-arrestin-1, Fab30 heavy chain, ... | Authors: | Staus, D.P, Hu, H, Robertson, M.J, Kleinhenz, A.L.W, Wingler, L.M, Capel, W.D, Latorraca, N.R, Lefkowitz, R.J, Skiniotis, G. | Deposit date: | 2019-08-16 | Release date: | 2020-02-26 | Last modified: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of the M2 muscarinic receptor-beta-arrestin complex in a lipid nanodisc. Nature, 579, 2020
|
|
6UCE
| |
6UE7
| Structure of dimeric sIgA complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L. | Deposit date: | 2019-09-20 | Release date: | 2020-02-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the secretory immunoglobulin A core. Science, 367, 2020
|
|
6UCF
| |
6UEA
| Structure of pentameric sIgA complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L. | Deposit date: | 2019-09-20 | Release date: | 2020-02-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the secretory immunoglobulin A core. Science, 367, 2020
|
|