6UDJ

HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074

This is a non-PDB format compatible entry.

Summary for 6UDJ

• Entry DOI: 10.2210/pdb6udj/pdb
• EMDB information: 20739 20740
• Descriptor: 10-1074 Fab Heavy Chain, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• Functional Keywords: hiv-1 broadly neutralizing antibody, env, cryo-em, bnab, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 18
• Total formula weight: 629041.90

Authors

Abernathy, M.E.,Barnes, C.O.,Gristick, H.B.,Bjorkman, P.J. (deposition date: 2019-09-19, release date: 2020-01-29, Last modification date: 2020-07-29)

• Primary citation: Schommers, P.,Gruell, H.,Abernathy, M.E.,Tran, M.K.,Dingens, A.S.,Gristick, H.B.,Barnes, C.O.,Schoofs, T.,Schlotz, M.,Vanshylla, K.,Kreer, C.,Weiland, D.,Holtick, U.,Scheid, C.,Valter, M.M.,van Gils, M.J.,Sanders, R.W.,Vehreschild, J.J.,Cornely, O.A.,Lehmann, C.,Fatkenheuer, G.,Seaman, M.S.,Bloom, J.D.,Bjorkman, P.J.,Klein, F.; Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.; Cell, 180:471-, 2020; PubMed: 32004464; DOI: 10.1016/j.cell.2020.01.010

Experimental method

ELECTRON MICROSCOPY (2.5 Å)