6UBI
N123-VRC34.05 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Summary for 6UBI
Entry DOI | 10.2210/pdb6ubi/pdb |
Descriptor | VRC34.05 heavy chain, VRC34.05 light chain, HIV fusion peptide 512-519, ... (4 entities in total) |
Functional Keywords | hiv, neutralizing, antibody, fusion peptide, immune system-viral protein, immune system-viral protein complex, immune system/viral protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 97006.31 |
Authors | Xu, K.,Liu, K.,Kwong, P.D. (deposition date: 2019-09-11, release date: 2020-03-18, Last modification date: 2020-04-22) |
Primary citation | Shen, C.H.,DeKosky, B.J.,Guo, Y.,Xu, K.,Gu, Y.,Kilam, D.,Ko, S.H.,Kong, R.,Liu, K.,Louder, M.K.,Ou, L.,Zhang, B.,Chao, C.W.,Corcoran, M.M.,Feng, E.,Huang, J.,Normandin, E.,O'Dell, S.,Ransier, A.,Rawi, R.,Sastry, M.,Schmidt, S.D.,Wang, S.,Wang, Y.,Chuang, G.Y.,Doria-Rose, N.A.,Lin, B.,Zhou, T.,Boritz, E.A.,Connors, M.,Douek, D.C.,Karlsson Hedestam, G.B.,Sheng, Z.,Shapiro, L.,Mascola, J.R.,Kwong, P.D. VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage. Cell Host Microbe, 27:531-, 2020 Cited by PubMed: 32130953DOI: 10.1016/j.chom.2020.01.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.903 Å) |
Structure validation
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