2ZNX

5-Fluorotryptophan Incorporated ScFv10 Complexed to Hen Egg Lysozyme

Summary for 2ZNX

• Entry DOI: 10.2210/pdb2znx/pdb
• Related: 2ZNW
• Descriptor: ScFv, Lysozyme C, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ... (4 entities in total)
• Functional Keywords: fluorotryptohpan, 5-fluorotryptophan, 19f, single chain fv, lysozyme, allergen, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase, immune system-hydrolase complex, immune system/hydrolase
• Biological source: Mus musculus (mouse); More
• Cellular location: Secreted: P00698
• Total number of polymer chains: 4
• Total formula weight: 81707.75

Authors

DeSantis, M.E.,Acchione, M.,Li, M.,Walter, R.L.,Wlodawer, A.,Smith-Gill, S. (deposition date: 2008-05-02, release date: 2009-01-27, Last modification date: 2023-11-01)

• Primary citation: Acchione, M.,Lee, Y.C.,DeSantis, M.E.,Lipschultz, C.A.,Wlodawer, A.,Li, M.,Shanmuganathan, A.,Walter, R.L.,Smith-Gill, S.,Barchi, J.J.; Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics; Biochemistry, 51:6017-6027, 2012; PubMed: 22769726; DOI: 10.1021/bi300455t

Experimental method

X-RAY DIFFRACTION (2.3 Å)