2ZNX

5-Fluorotryptophan Incorporated ScFv10 Complexed to Hen Egg Lysozyme

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002250	biological_process	adaptive immune response
A	0003823	molecular_function	antigen binding
A	0003964	molecular_function	RNA-directed DNA polymerase activity
A	0005615	cellular_component	extracellular space
A	0006278	biological_process	RNA-templated DNA biosynthetic process
A	0006955	biological_process	immune response
A	0016064	biological_process	immunoglobulin mediated immune response
A	0019814	cellular_component	immunoglobulin complex
A	0072562	cellular_component	blood microparticle
B	0002250	biological_process	adaptive immune response
B	0003823	molecular_function	antigen binding
B	0003964	molecular_function	RNA-directed DNA polymerase activity
B	0005615	cellular_component	extracellular space
B	0006278	biological_process	RNA-templated DNA biosynthetic process
B	0006955	biological_process	immune response
B	0016064	biological_process	immunoglobulin mediated immune response
B	0019814	cellular_component	immunoglobulin complex
B	0072562	cellular_component	blood microparticle
Y	0003796	molecular_function	lysozyme activity
Y	0005515	molecular_function	protein binding
Y	0005576	cellular_component	extracellular region
Y	0005615	cellular_component	extracellular space
Y	0005737	cellular_component	cytoplasm
Y	0005783	cellular_component	endoplasmic reticulum
Y	0016231	molecular_function	beta-N-acetylglucosaminidase activity
Y	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
Y	0016998	biological_process	cell wall macromolecule catabolic process
Y	0031640	biological_process	killing of cells of another organism
Y	0042742	biological_process	defense response to bacterium
Y	0042802	molecular_function	identical protein binding
Y	0050829	biological_process	defense response to Gram-negative bacterium
Y	0050830	biological_process	defense response to Gram-positive bacterium
Y	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
Z	0003796	molecular_function	lysozyme activity
Z	0005515	molecular_function	protein binding
Z	0005576	cellular_component	extracellular region
Z	0005615	cellular_component	extracellular space
Z	0005737	cellular_component	cytoplasm
Z	0005783	cellular_component	endoplasmic reticulum
Z	0016231	molecular_function	beta-N-acetylglucosaminidase activity
Z	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
Z	0016998	biological_process	cell wall macromolecule catabolic process
Z	0031640	biological_process	killing of cells of another organism
Z	0042742	biological_process	defense response to bacterium
Z	0042802	molecular_function	identical protein binding
Z	0050829	biological_process	defense response to Gram-negative bacterium
Z	0050830	biological_process	defense response to Gram-positive bacterium
Z	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 1PG B 243

Chain	Residue
B	HIS34
B	TYR36
B	TYR50
B	GLN89
B	SER91
B	ASP221
Z	ILE78

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 1PG A 243

Chain	Residue
A	TYR50
A	GLN89
A	ASP221
Y	CYS76
Y	ASN93
A	HIS34
A	TYR36

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Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC

Chain	Residue	Details
Y	CYS76-CYS94

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE:

Chain	Residue	Details
Y	GLU35
Y	ASP52
Z	GLU35
Z	ASP52

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
Y	ASP101
Z	ASP101

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 132l

Chain	Residue	Details
Y	GLU35
Y	ASP52

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 132l

Chain	Residue	Details
Z	GLU35
Z	ASP52

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site_id	MCSA1
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
Y	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
Y	ASN46
Y	ASP48
Y	SER50
Y	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
Y	ASN59

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site_id	MCSA2
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
Z	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
Z	ASN46
Z	ASP48
Z	SER50
Z	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
Z	ASN59

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