6U1N

GPCR-Beta arrestin structure in lipid bilayer

Summary for 6U1N

• Entry DOI: 10.2210/pdb6u1n/pdb
• EMDB information: 20612
• Descriptor: Muscarinic acetylcholine receptor M2, Vasopressin V2 receptor chimera, Beta-arrestin-1, Fab30 heavy chain, ... (5 entities in total)
• Functional Keywords: arrestin, gpcr, complex, signaling, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 151018.72

Authors

Staus, D.P.,Hu, H.,Robertson, M.J.,Kleinhenz, A.L.W.,Wingler, L.M.,Capel, W.D.,Latorraca, N.R.,Lefkowitz, R.J.,Skiniotis, G. (deposition date: 2019-08-16, release date: 2020-02-26, Last modification date: 2020-03-25)

• Primary citation: Staus, D.P.,Hu, H.,Robertson, M.J.,Kleinhenz, A.L.W.,Wingler, L.M.,Capel, W.D.,Latorraca, N.R.,Lefkowitz, R.J.,Skiniotis, G.; Structure of the M2 muscarinic receptor-beta-arrestin complex in a lipid nanodisc.; Nature, 579:297-302, 2020; PubMed: 31945772; DOI: 10.1038/s41586-020-1954-0

Experimental method

ELECTRON MICROSCOPY (4 Å)