1NDG
 
 | | Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme | | Descriptor: | ACETIC ACID, Lysozyme C, antibody kappa light chain, ... | | Authors: | Mariuzza, R.A, Li, Y, Li, H, Yang, F, Smith-Gill, S.J. | | Deposit date: | 2002-12-09 | | Release date: | 2003-06-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
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4ZTO
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3S62
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4AEH
 | | Crystal structure of the anti-AaHI Fab9C2 antibody | | Descriptor: | FAB ANTIBODY, HEAVY CHAIN, LIGHT CHAIN | | Authors: | Fabrichny, I.P, Mondielli, G, Conrod, S, Martin-Eauclaire, M.F, Bourne, Y, Marchot, P. | | Deposit date: | 2012-01-10 | | Release date: | 2012-03-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom
J.Biol.Chem., 287, 2012
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6GK8
 | | Crystal structure of anti-tau antibody dmCBTAU-28.1, double mutant (S32R, E35K) of CBTAU-28.1, in complex with Tau peptide A7731 (residues 52-71) | | Descriptor: | CHLORIDE ION, HUMAN FAB ANTIBODY FRAGMENT OF CBTAU-28.1(S32R;E35K), TAU PEPTIDE A7731 (RESIDUES 52-71) | | Authors: | Steinbacher, S, Mrosek, M, Juraszek, J. | | Deposit date: | 2018-05-18 | | Release date: | 2018-06-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
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6GK7
 | | Crystal structure of anti-tau antibody dmCBTAU-27.1, double mutant (S31Y, T100I) of CBTAU-27.1, in complex with Tau peptide A8119B (residues 299-318) | | Descriptor: | CHLORIDE ION, HUMAN FAB ANTIBODY FRAGMENT OF CBTAU-27.1(S31Y,T100I), HUMAN TAU PEPTIDE A8119 RESIDUES 299-318 | | Authors: | Steinbacher, S, Mrosek, M, Juraszek, J. | | Deposit date: | 2018-05-18 | | Release date: | 2018-06-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
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5D93
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7BWJ
 | | crystal structure of SARS-CoV-2 antibody with RBD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | | Authors: | Wang, X, Ge, J. | | Deposit date: | 2020-04-14 | | Release date: | 2020-06-03 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Human neutralizing antibodies elicited by SARS-CoV-2 infection.
Nature, 584, 2020
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3VGA
 | | Crystal structure of human adenosine A2A receptor with an allosteric inverse-agonist antibody at 3.1 A resolution | | Descriptor: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a, antibody fab fragment heavy chain, ... | | Authors: | Hino, T, Arakawa, T, Iwanari, H, Yurugi-Kobayashi, T, Ikeda-Suno, C, Nakada-Nakura, Y, Kusano-Arai, O, Weyand, S, Shimamura, T, Nomura, N, Cameron, A.D, Kobayashi, T, Hamakubo, T, Iwata, S, Murata, T. | | Deposit date: | 2011-08-04 | | Release date: | 2012-02-01 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
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4DAG
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1NDM
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2XQB
 | | Crystal Structure of anti-IL-15 Antibody in Complex with human IL-15 | | Descriptor: | ANTI-IL-15 ANTIBODY, INTERLEUKIN 15, SULFATE ION | | Authors: | Lowe, D.C, Gerhardt, S, Ward, A, Hargreaves, D, Anderson, M, StGallay, S, Vousden, K, Ferraro, F, Pauptit, R.A, Cochrane, D, Pattison, D.V, Buchanan, C, Popovic, B, Finch, D.K, Wilkinson, T, Sleeman, M, Vaughan, T.J, Cruwys, S, Mallinder, P.R. | | Deposit date: | 2010-09-01 | | Release date: | 2010-12-29 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Engineering a High Affinity Anti-Il-15 Antibody: Crystal Structure Reveals an Alpha-Helix in Vh Cdr3 as Key Component of Paratope.
J.Mol.Biol., 406, 2011
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5D96
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3RPI
 | | Crystal Structure of Fab from 3BNC60, Highly Potent anti-HIV Antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from highly potent anti-HIV neutralizing antibody, Light chain from highly potent anti-HIV neutralizing antibody | | Authors: | Diskin, R, Bjorkman, P.J. | | Deposit date: | 2011-04-26 | | Release date: | 2011-07-20 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.648 Å) | | Cite: | Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.
Science, 333, 2011
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3MUG
 | | Crystal structure of human Fab PG16, a broadly reactive and potent HIV-1 neutralizing antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody PG16 Heavy Chain, ... | | Authors: | Pejchal, R, Walker, L.M, Burton, D.R, Wilson, I.A. | | Deposit date: | 2010-05-03 | | Release date: | 2010-06-16 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3VG9
 | | Crystal structure of human adenosine A2A receptor with an allosteric inverse-agonist antibody at 2.7 A resolution | | Descriptor: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Hino, T, Arakawa, T, Iwanari, H, Yurugi-Kobayashi, T, Ikeda-Suno, C, Nakada-Nakura, Y, Kusano-Arai, O, Weyand, S, Shimamura, T, Nomura, N, Cameron, A.D, Kobayashi, T, Hamakubo, T, Iwata, S, Murata, T. | | Deposit date: | 2011-08-04 | | Release date: | 2012-02-01 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
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3UC0
 | | Crystal structure of domain I of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2 | | Descriptor: | GLYCEROL, Heavy chain, monoclonal antibody 5H2, ... | | Authors: | Cockburn, J.J.B, Stura, E.A, Navarro-Sanchez, M.E, Rey, F.A. | | Deposit date: | 2011-10-25 | | Release date: | 2011-12-14 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus.
Embo J., 31, 2012
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3FFD
 | | Structure of parathyroid hormone-related protein complexed to a neutralizing monoclonal antibody | | Descriptor: | Monoclonal antibody, heavy chain, Fab fragment, ... | | Authors: | Mckinstry, W.J, Polekhina, G, Diefenbach-Jagger, H, Ho, P.W.M, Sato, K, Onuma, E, Gillespie, M.T, Martin, T.J, Parker, M.W. | | Deposit date: | 2008-12-03 | | Release date: | 2009-04-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for antibody discrimination between two hormones that recognize the parathyroid hormone receptor
J.Biol.Chem., 284, 2009
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5LBS
 | | structural basis of Zika and Dengue virus potent antibody cross-neutralization | | Descriptor: | 1,2-ETHANEDIOL, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8, SULFATE ION, ... | | Authors: | Vaney, M.C, Rouvinski, A, Barba-Spaeth, G, Rey, F.A. | | Deposit date: | 2016-06-17 | | Release date: | 2016-07-06 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Structural basis of potent Zika-dengue virus antibody cross-neutralization.
Nature, 536, 2016
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4U05
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4TYU
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4C2I
 | | Cryo-EM structure of Dengue virus serotype 1 complexed with Fab fragments of human antibody 1F4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Fibriansah, G, Tan, J.L, de Alwis, R, Smith, S.A, Ng, T.-S, Kostyuchenko, V.A, Ibarra, K.D, Harris, E, de Silva, A, Crowe Junior, J.E, Lok, S.-M. | | Deposit date: | 2013-08-18 | | Release date: | 2014-01-29 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | A Potent Anti-Dengue Human Antibody Preferentially Recognizes the Conformation of E Protein Monomers Assembled on the Virus Surface.
Embo Mol.Med., 6, 2014
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1RI8
 | | Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme | | Descriptor: | GLYCEROL, Lysozyme C, camelid ANTIBODY HEAVY CHAIN | | Authors: | De Genst, E, Silence, K, Ghahroudi, M.A, Decanniere, K, Loris, R, Kinne, J, Wyns, L, Muyldermans, S. | | Deposit date: | 2003-11-17 | | Release date: | 2005-02-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.
J.Biol.Chem., 280, 2005
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4YDV
 | | STRUCTURE OF THE ANTIBODY 7B2 THAT CAPTURES HIV-1 VIRIONS | | Descriptor: | HIV ANTIBODY 7B2 HEAVY CHAIN,IgG H chain, HIV ANTIBODY 7B2 LIGHT CHAIN,Ig kappa chain C region, HIV GP41 PEPTIDE GP41(596-606) | | Authors: | Nicely, N.I, Pemble IV, C.W. | | Deposit date: | 2015-02-23 | | Release date: | 2015-08-12 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.
Plos Pathog., 11, 2015
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3GKW
 | | Crystal structure of the Fab fragment of Nimotuzumab. An anti-epidermal growth factor receptor antibody | | Descriptor: | DI(HYDROXYETHYL)ETHER, Heavy chain of the antibody Nimotuzumab, Light chain of the antibody Nimotuzumab, ... | | Authors: | Talavera, A, Friemann, R, Martinez-Fleites, C, Moreno, E, Krengel, U. | | Deposit date: | 2009-03-11 | | Release date: | 2009-08-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation
Cancer Res., 69, 2009
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