4C2I

Cryo-EM structure of Dengue virus serotype 1 complexed with Fab fragments of human antibody 1F4

Summary for 4C2I

Entry DOI	10.2210/pdb4c2i/pdb
EMDB information	2442
Related PRD ID	PRD_900017
Descriptor	ENVELOPE PROTEIN, POLYPROTEIN, HEAVY CHAIN FAB FRAGMENT OF ANTIBODY 1F4, ... (7 entities in total)
Functional Keywords	virus, e proteins, neutralization
Biological source	DENGUE VIRUS 1 More
Total number of polymer chains	10
Total formula weight	289287.33
Authors	Fibriansah, G.,Tan, J.L.,de Alwis, R.,Smith, S.A.,Ng, T.-S.,Kostyuchenko, V.A.,Ibarra, K.D.,Harris, E.,de Silva, A.,Crowe Junior, J.E.,Lok, S.-M. (deposition date: 2013-08-18, release date: 2014-01-29, Last modification date: 2020-07-29)
Primary citation	Fibriansah, G.,Tan, J.L.,Smith, S.A.,De Alwis, A.R.,Ng, T.,Kostyuchenko, V.A.,Ibarra, K.D.,Wang, J.,Harris, E.,De Silva, A.,Crowe, J.E.J.,Lok, S. A Potent Anti-Dengue Human Antibody Preferentially Recognizes the Conformation of E Protein Monomers Assembled on the Virus Surface. Embo Mol.Med., 6:358-, 2014 Cited by PubMed: 24421336 DOI: 10.1002/EMMM.201303404 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (6 Å)

Structure validation