4C2I
Cryo-EM structure of Dengue virus serotype 1 complexed with Fab fragments of human antibody 1F4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | ENVELOPE PROTEIN | polymer | 495 | 53894.8 | 3 | UniProt (Q7TGE4) | DENGUE VIRUS 1 | |
| 2 | B, D, F (B, D, F) | POLYPROTEIN | polymer | 75 | 8081.5 | 3 | UniProt (G3F5K5) | DENGUE VIRUS 1 | |
| 3 | G, I (H, M) | HEAVY CHAIN FAB FRAGMENT OF ANTIBODY 1F4 | polymer | 232 | 24835.9 | 2 | HOMO SAPIENS (HUMAN) | ||
| 4 | H, J (L, N) | LIGHT CHAIN FAB FRAGMENT OF ANTIBODY 1F4 | polymer | 239 | 25468.6 | 2 | HOMO SAPIENS (HUMAN) | ||
| 5 | K, N (G, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 2 | In PDB BIRD (PRD_900017) GlyTouCan (G47362BJ) | triacetyl-beta-chitotriose | ||
| 6 | L, M, O (I, J, O) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 7 | P (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A, C, E: 1 - 495 (UniProt: Q7TGE4)
| PDB | External Database | Details |
|---|---|---|
| Ser 7 | Gly 7 | conflict |
| Asn 8 | Ser 8 | conflict |
| Ala 17 | Gly 17 | conflict |
| Thr 18 | Ala 18 | conflict |
| Gly 19 | Thr 19 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 286537.7 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2528.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 289287.3 |
