4C2I

Cryo-EM structure of Dengue virus serotype 1 complexed with Fab fragments of human antibody 1F4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019031	cellular_component	viral envelope
A	0019062	biological_process	virion attachment to host cell
A	0039654	biological_process	fusion of virus membrane with host endosome membrane
A	0039663	biological_process	membrane fusion involved in viral entry into host cell
A	0044167	cellular_component	host cell endoplasmic reticulum membrane
A	0044423	cellular_component	virion component
A	0046718	biological_process	symbiont entry into host cell
A	0046983	molecular_function	protein dimerization activity
A	0052031	biological_process	symbiont-mediated perturbation of host defense response
A	0052170	biological_process	symbiont-mediated suppression of host innate immune response
A	0055036	cellular_component	virion membrane
A	0075509	biological_process	endocytosis involved in viral entry into host cell
A	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell
B	0019058	biological_process	viral life cycle
C	0019031	cellular_component	viral envelope
C	0019062	biological_process	virion attachment to host cell
C	0039654	biological_process	fusion of virus membrane with host endosome membrane
C	0039663	biological_process	membrane fusion involved in viral entry into host cell
C	0044167	cellular_component	host cell endoplasmic reticulum membrane
C	0044423	cellular_component	virion component
C	0046718	biological_process	symbiont entry into host cell
C	0046983	molecular_function	protein dimerization activity
C	0052031	biological_process	symbiont-mediated perturbation of host defense response
C	0052170	biological_process	symbiont-mediated suppression of host innate immune response
C	0055036	cellular_component	virion membrane
C	0075509	biological_process	endocytosis involved in viral entry into host cell
C	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell
D	0019058	biological_process	viral life cycle
E	0019031	cellular_component	viral envelope
E	0019062	biological_process	virion attachment to host cell
E	0039654	biological_process	fusion of virus membrane with host endosome membrane
E	0039663	biological_process	membrane fusion involved in viral entry into host cell
E	0044167	cellular_component	host cell endoplasmic reticulum membrane
E	0044423	cellular_component	virion component
E	0046718	biological_process	symbiont entry into host cell
E	0046983	molecular_function	protein dimerization activity
E	0052031	biological_process	symbiont-mediated perturbation of host defense response
E	0052170	biological_process	symbiont-mediated suppression of host innate immune response
E	0055036	cellular_component	virion membrane
E	0075509	biological_process	endocytosis involved in viral entry into host cell
E	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell
F	0019058	biological_process	viral life cycle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
L	TYR218-HIS224
H	TYR210-HIS216

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