5D93

Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody

Summary for 5D93

• Entry DOI: 10.2210/pdb5d93/pdb
• Related: 5D8I
• Descriptor: Sulfhydryl oxidase 1, Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, ... (4 entities in total)
• Functional Keywords: enzyme, inhibitor, thioredoxin fold, antibody, oxidoreductase
• Biological source: Mus musculus (Mouse); More
• Cellular location: Isoform 1: Golgi apparatus membrane ; Single-pass membrane protein . Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted: Q8BND5
• Total number of polymer chains: 6
• Total formula weight: 147248.70

Authors

Grossman, I.,Fass, D. (deposition date: 2015-08-18, release date: 2016-02-10, Last modification date: 2024-01-10)

• Primary citation: Grossman, I.,Ilani, T.,Fleishman, S.J.,Fass, D.; Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.; Protein Eng.Des.Sel., 29:135-147, 2016; PubMed: 26819240; DOI: 10.1093/protein/gzv067

Experimental method

X-RAY DIFFRACTION (2.201 Å)