5LBS

structural basis of Zika and Dengue virus potent antibody cross-neutralization

Summary for 5LBS

• Entry DOI: 10.2210/pdb5lbs/pdb
• Related: 4UTA 4UTB
• Descriptor: envelope protein E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: immune system-viral protein complex, zika virus, broadly neutralizing antibody, immune system-viral protein
• Biological source: Zika virus (ZIKV); More
• Total number of polymer chains: 6
• Total formula weight: 158934.27

Authors

Vaney, M.C.,Rouvinski, A.,Barba-Spaeth, G.,Rey, F.A. (deposition date: 2016-06-17, release date: 2016-07-06, Last modification date: 2024-01-10)

• Primary citation: Barba-Spaeth, G.,Dejnirattisai, W.,Rouvinski, A.,Vaney, M.C.,Medits, I.,Sharma, A.,Simon-Loriere, E.,Sakuntabhai, A.,Cao-Lormeau, V.M.,Haouz, A.,England, P.,Stiasny, K.,Mongkolsapaya, J.,Heinz, F.X.,Screaton, G.R.,Rey, F.A.; Structural basis of potent Zika-dengue virus antibody cross-neutralization.; Nature, 536:48-53, 2016; PubMed: 27338953; DOI: 10.1038/nature18938

Experimental method

X-RAY DIFFRACTION (2.41 Å)