5LBS
structural basis of Zika and Dengue virus potent antibody cross-neutralization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | envelope protein E | polymer | 447 | 48492.5 | 2 | UniProt (A0A120IIH9) Pfam (PF00869) Pfam (PF02832) UniProt (by SIFTS) (A0A024B7W1) | Zika virus (ZIKV) | |
| 2 | C, D (H, I) | BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 | polymer | 141 | 14617.8 | 2 | Homo sapiens (HUMAN) | ||
| 3 | E, F (L, M) | BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 | polymer | 147 | 15871.4 | 2 | Homo sapiens (HUMAN) | ||
| 4 | G, H, I, L, M... (A, H, I, L, M) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 5 | J, K, O (A, B, I) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | U, V, W, X, Y... (A, B, H, I, L...) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 408 (UniProt: A0A120IIH9)
| PDB | External Database | Details |
|---|---|---|
| Gly 409 | - | expression tag |
| Pro 410 | - | expression tag |
| Phe 411 | - | expression tag |
| Glu 412 | - | expression tag |
| Asp 413 | - | expression tag |
| Asp 414 | - | expression tag |
| Asp 415 | - | expression tag |
| Asp 416 | - | expression tag |
| Lys 417 | - | expression tag |
| Ala 418 | - | expression tag |
| Gly 419 | - | expression tag |
| Trp 420 | - | expression tag |
| Ser 421 | - | expression tag |
| His 422 | - | expression tag |
| Pro 423 | - | expression tag |
| Gln 424 | - | expression tag |
| Phe 425 | - | expression tag |
| Glu 426 | - | expression tag |
| Lys 427 | - | expression tag |
| Gly 428 | - | expression tag |
| Gly 429 | - | expression tag |
| Gly 430 | - | expression tag |
| Ser 431 | - | expression tag |
| Gly 432 | - | expression tag |
| Gly 433 | - | expression tag |
| Gly 434 | - | expression tag |
| Ser 435 | - | expression tag |
| Gly 436 | - | expression tag |
| Gly 437 | - | expression tag |
| Gly 438 | - | expression tag |
| Ser 439 | - | expression tag |
| Trp 440 | - | expression tag |
| Ser 441 | - | expression tag |
| His 442 | - | expression tag |
| Pro 443 | - | expression tag |
| Gln 444 | - | expression tag |
| Phe 445 | - | expression tag |
| Glu 446 | - | expression tag |
| Lys 447 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 157963.3 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 970.9 | |
| All* | Total formula weight | 158934.3 |
