1RI8

Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme

Summary for 1RI8

Entry DOI	10.2210/pdb1ri8/pdb
Descriptor	camelid ANTIBODY HEAVY CHAIN, Lysozyme C, GLYCEROL, ... (4 entities in total)
Functional Keywords	beta sandwich, immunoglobulin fold, vhh-lysozyme complex, alpha-beta orthogonal bundle, immune system-hydrolase complex, immune system/hydrolase
Biological source	Camelus dromedarius (Arabian camel) More
Cellular location	Secreted: P00698
Total number of polymer chains	2
Total formula weight	29140.53
Authors	De Genst, E.,Silence, K.,Ghahroudi, M.A.,Decanniere, K.,Loris, R.,Kinne, J.,Wyns, L.,Muyldermans, S. (deposition date: 2003-11-17, release date: 2005-02-01, Last modification date: 2011-07-13)
Primary citation	De Genst, E.,Silence, K.,Ghahroudi, M.A.,Decanniere, K.,Loris, R.,Kinne, J.,Wyns, L.,Muyldermans, S. Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. J.Biol.Chem., 280:14114-14121, 2005 Cited by PubMed: 15659390 DOI: 10.1074/jbc.M413011200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation