4AEH

Crystal structure of the anti-AaHI Fab9C2 antibody

Summary for 4AEH

• Entry DOI: 10.2210/pdb4aeh/pdb
• Descriptor: FAB ANTIBODY, HEAVY CHAIN, FAB ANTIBODY, LIGHT CHAIN (3 entities in total)
• Functional Keywords: immune system, androctonus, alpha-toxin, combining site, epitope, pharmacological site, venom, voltage- activated sodium channel, scorpion
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Total number of polymer chains: 2
• Total formula weight: 48202.39

Authors

Fabrichny, I.P.,Mondielli, G.,Conrod, S.,Martin-Eauclaire, M.F.,Bourne, Y.,Marchot, P. (deposition date: 2012-01-10, release date: 2012-03-07, Last modification date: 2012-05-02)

• Primary citation: Fabrichny, I.P.,Mondielli, G.,Conrod, S.,Martin-Eauclaire, M.F.,Bourne, Y.,Marchot, P.; Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom; J.Biol.Chem., 287:14136-, 2012; PubMed: 22371498; DOI: 10.1074/JBC.M111.315382

Experimental method

X-RAY DIFFRACTION (1.6 Å)