3RPI

Crystal Structure of Fab from 3BNC60, Highly Potent anti-HIV Antibody

Summary for 3RPI

Entry DOI	10.2210/pdb3rpi/pdb
Descriptor	Light chain from highly potent anti-HIV neutralizing antibody, Heavy chain from highly potent anti-HIV neutralizing antibody, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	igg, glycosylation, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	96411.41
Authors	Diskin, R.,Bjorkman, P.J. (deposition date: 2011-04-26, release date: 2011-07-20, Last modification date: 2020-07-29)
Primary citation	Scheid, J.F.,Mouquet, H.,Ueberheide, B.,Diskin, R.,Klein, F.,Oliveira, T.Y.,Pietzsch, J.,Fenyo, D.,Abadir, A.,Velinzon, K.,Hurley, A.,Myung, S.,Boulad, F.,Poignard, P.,Burton, D.R.,Pereyra, F.,Ho, D.D.,Walker, B.D.,Seaman, M.S.,Bjorkman, P.J.,Chait, B.T.,Nussenzweig, M.C. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science, 333:1633-1637, 2011 Cited by PubMed: 21764753 DOI: 10.1126/science.1207227 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.648 Å)

Structure validation