6YBW
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![BU of 6ybw by Molmil](/molmil-images/mine/6ybw) | Structure of a human 48S translational initiation complex - 40S body | Descriptor: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | Authors: | Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. | Deposit date: | 2020-03-18 | Release date: | 2020-09-16 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of a human 48Stranslational initiation complex. Science, 369, 2020
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8T4S
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6G4W
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![BU of 6g4w by Molmil](/molmil-images/mine/6g4w) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State A | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-28 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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6G51
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![BU of 6g51 by Molmil](/molmil-images/mine/6g51) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State D | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-28 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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6G53
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![BU of 6g53 by Molmil](/molmil-images/mine/6g53) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State E | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-28 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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6FT6
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![BU of 6ft6 by Molmil](/molmil-images/mine/6ft6) | Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors | Descriptor: | 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ... | Authors: | Schuller, J.M, Falk, S, Conti, E. | Deposit date: | 2018-02-20 | Release date: | 2018-03-28 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
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6FF7
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![BU of 6ff7 by Molmil](/molmil-images/mine/6ff7) | human Bact spliceosome core structure | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | Authors: | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | Deposit date: | 2018-01-03 | Release date: | 2019-03-13 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
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7OBR
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![BU of 7obr by Molmil](/molmil-images/mine/7obr) | RNC-SRP early complex | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Jomaa, A, Ban, N. | Deposit date: | 2021-04-23 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle. Cell Rep, 36, 2021
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8OJ8
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![BU of 8oj8 by Molmil](/molmil-images/mine/8oj8) | 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | Deposit date: | 2023-03-24 | Release date: | 2024-02-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
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6Y53
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![BU of 6y53 by Molmil](/molmil-images/mine/6y53) | human 17S U2 snRNP low resolution part | Descriptor: | HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ... | Authors: | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | Deposit date: | 2020-02-24 | Release date: | 2020-06-17 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
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6J9E
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![BU of 6j9e by Molmil](/molmil-images/mine/6j9e) | |
6G5H
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![BU of 6g5h by Molmil](/molmil-images/mine/6g5h) | Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-29 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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6Q8Y
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![BU of 6q8y by Molmil](/molmil-images/mine/6q8y) | Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Heckel, E, Cheng, J, Buschauer, R, Kater, L, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2018-12-16 | Release date: | 2019-03-13 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the 80S ribosome-Xrn1 nuclease complex. Nat.Struct.Mol.Biol., 26, 2019
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8B5L
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![BU of 8b5l by Molmil](/molmil-images/mine/8b5l) | Cryo-EM structure of ribosome-Sec61-TRAP (TRanslocon Associated Protein) translocon complex | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K. | Deposit date: | 2022-09-23 | Release date: | 2023-03-01 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative. Sci Adv, 9, 2023
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8B6C
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![BU of 8b6c by Molmil](/molmil-images/mine/8b6c) | Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147 | Descriptor: | 28S rRNA, 4-[[9-(cyclohexylmethyl)-3-methylidene-5-(4-methylphenyl)sulfonyl-1,5,9-triazacyclododec-1-yl]sulfonyl]-~{N},~{N}-dimethyl-aniline, 5.8S rRNA, ... | Authors: | Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K. | Deposit date: | 2022-09-26 | Release date: | 2023-02-22 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative. Sci Adv, 9, 2023
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6J9F
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2DTU
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![BU of 2dtu by Molmil](/molmil-images/mine/2dtu) | Crystal structure of the beta hairpin loop deletion variant of RB69 gp43 in complex with DNA containing an abasic site analog | Descriptor: | 5'-D(*CP*GP*(3DR)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*GP*A)-3', DNA polymerase | Authors: | Aller, P, Hogg, M, Konigsberg, W, Wallace, S.S, Doublie, S. | Deposit date: | 2006-07-15 | Release date: | 2006-12-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. J.Biol.Chem., 282, 2007
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6QW6
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![BU of 6qw6 by Molmil](/molmil-images/mine/6qw6) | Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Charenton, C, Wilkinson, M.E, Nagai, K. | Deposit date: | 2019-03-05 | Release date: | 2019-04-17 | Last modified: | 2020-10-07 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
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6WCZ
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![BU of 6wcz by Molmil](/molmil-images/mine/6wcz) | CryoEM structure of full-length ZIKV NS5-hSTAT2 complex | Descriptor: | Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION | Authors: | Boxiao, W, Stephanie, T, Kang, Z, Maria, T.S, Jian, F, Jiuwei, L, Linfeng, G, Wendan, R, Yanxiang, C, Ethan, C.V, HeaJin, H, Matthew, J.E, Sean, E.O, Adolfo, G.S, Hong, Z, Rong, H, Jikui, S. | Deposit date: | 2020-03-31 | Release date: | 2020-07-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis for STAT2 suppression by flavivirus NS5. Nat.Struct.Mol.Biol., 27, 2020
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7EVO
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![BU of 7evo by Molmil](/molmil-images/mine/7evo) | The cryo-EM structure of the human 17S U2 snRNP | Descriptor: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ... | Authors: | Zhang, X, Zhan, X, Shi, Y. | Deposit date: | 2021-05-21 | Release date: | 2022-08-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
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6YBS
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![BU of 6ybs by Molmil](/molmil-images/mine/6ybs) | Structure of a human 48S translational initiation complex - head | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... | Authors: | Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. | Deposit date: | 2020-03-17 | Release date: | 2020-09-16 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of a human 48Stranslational initiation complex. Science, 369, 2020
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8Y7E
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![BU of 8y7e by Molmil](/molmil-images/mine/8y7e) | Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part | Descriptor: | PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... | Authors: | Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. | Deposit date: | 2024-02-04 | Release date: | 2024-03-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.66 Å) | Cite: | Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome. Science, 383, 2024
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8RC0
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![BU of 8rc0 by Molmil](/molmil-images/mine/8rc0) | Structure of the human 20S U5 snRNP | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Schneider, S, Galej, W.P. | Deposit date: | 2023-12-05 | Release date: | 2024-03-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of the human 20S U5 snRNP. Nat.Struct.Mol.Biol., 31, 2024
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8IGR
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![BU of 8igr by Molmil](/molmil-images/mine/8igr) | Cryo-EM structure of CII-dependent transcription activation complex | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y. | Deposit date: | 2023-02-21 | Release date: | 2023-05-17 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of lambda CII-dependent transcription activation. Structure, 31, 2023
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2DY4
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![BU of 2dy4 by Molmil](/molmil-images/mine/2dy4) | Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol | Descriptor: | 5'-D(*CP*GP*(CTG)P*GP*GP*AP*AP*TP*GP*A*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*T*CP*AP*TP*TP*CP*CP*A)-3', DNA polymerase | Authors: | Aller, P, Rould, M.A, Hogg, M, Wallace, S.S, Doublie, S. | Deposit date: | 2006-09-06 | Release date: | 2007-01-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Proc.Natl.Acad.Sci.USA, 104, 2007
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