2DY4
Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol
Summary for 2DY4
Entry DOI | 10.2210/pdb2dy4/pdb |
Related | 1CLQ 1IG9 1Q9X 1Q9Y 1RV2 2DTU |
Descriptor | 5'-D(*CP*GP*(CTG)P*GP*GP*AP*AP*TP*GP*A*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*T*CP*AP*TP*TP*CP*CP*A)-3', DNA polymerase, ... (4 entities in total) |
Functional Keywords | dna polymerase, dna lesion, thymine glycol, oxidative thymine lesion, transferase-dna complex, transferase/dna |
Biological source | Enterobacteria phage RB69 |
Total number of polymer chains | 12 |
Total formula weight | 463956.60 |
Authors | Aller, P.,Rould, M.A.,Hogg, M.,Wallace, S.S.,Doublie, S. (deposition date: 2006-09-06, release date: 2007-01-09, Last modification date: 2023-11-15) |
Primary citation | Aller, P.,Rould, M.A.,Hogg, M.,Wallace, S.S.,Doublie, S. A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Proc.Natl.Acad.Sci.USA, 104:814-818, 2007 Cited by PubMed: 17210917DOI: 10.1073/pnas.0606648104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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