8T4S

MERS-CoV Nsp1 protein bound to the Human 40S Ribosomal subunit

Summary for 8T4S

Entry DOI	10.2210/pdb8t4s/pdb
EMDB information	41039 41063 41064 41065
Descriptor	18S rRNA, 40S ribosomal protein S8, 40S ribosomal protein S9, ... (39 entities in total)
Functional Keywords	mers-cov nsp1, translation inhibition, 40s ribosome, betacoronaviruses, ribosome, ribosome-viral protein complex, ribosome/viral protein
Biological source	Middle East respiratory syndrome-related coronavirus More
Total number of polymer chains	36
Total formula weight	1257354.76
Authors	Devarkar, S.C.,Xiong, Y. (deposition date: 2023-06-09, release date: 2023-10-04, Last modification date: 2023-10-11)
Primary citation	Devarkar, S.C.,Vetick, M.,Balaji, S.,Lomakin, I.B.,Yang, L.,Jin, D.,Gilbert, W.V.,Chen, S.,Xiong, Y. Structural basis for translation inhibition by MERS-CoV Nsp1 reveals a conserved mechanism for betacoronaviruses. Cell Rep, 42:113156-113156, 2023 Cited by PubMed: 37733586 DOI: 10.1016/j.celrep.2023.113156 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.6 Å)

Structure validation