6Q8Y

Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex

This is a large structure.

Summary for 6Q8Y

EMDB information4474
Descriptor18S ribosomal RNA, 60S ribosomal protein L8-A, 60S ribosomal protein L23-A, ... (84 entities in total)
Functional Keywordsribosome, stalling, translation, nuclease, exoribonuclease, xrn1
Biological sourceSaccharomyces cerevisiae
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Total number of polymer chains82
Total molecular weight3180012.67
Authors
Tesina, P.,Heckel, E.,Cheng, J.,Buschauer, R.,Kater, L.,Berninghausen, O.,Becker, T.,Beckmann, R. (deposition date: 2018-12-16, release date: 2019-03-13)
Primary citation
Tesina, P.,Heckel, E.,Cheng, J.,Buschauer, R.,Kater, L.,Berninghausen, O.,Fromont-Racine, M.,Beatrix, B.,Jacquier, A.,Becker, T.,Beckmann, R.
Structure of the 80S ribosome-Xrn1 nuclease complex
Nat.Struct.Mol.Biol., 2019
DOI: 10.1038/s41594-019-0202-5
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone3 0.5% 0.5% 0.53MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 6q8y
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Molmil generated image of 6q8y
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Molmil generated image of 6q8y
rotated about y axis by 90°